Advertisement

International Journal of Legal Medicine

, Volume 133, Issue 3, pp 771–773 | Cite as

Genetic diversities and phylogenetic analysis of 18 autosomal STR loci in the Uyghur population living in Ili, Northwest China

  • Zhenghui Li
  • Jian Zhang
  • Yiwen Zhang
  • Bin Kang
  • Wanshui Li
  • Xingchun Zhao
  • Ziqing Lin
  • Jian YeEmail author
Population Data

Abstract

Ili is located in northernmost Xinjiang, China. The Uyghur population only accounts for 15.90% of the total population in the nation. There is currently no large population data-based data set in Ili Uyghur. In this study, we investigated the genetic diversities of 18 autosomal short tandem repeat (STR) loci in 1129 Uyghur individuals living in Ili. The values of combined power of discrimination (CPD) and combined probability of exclusion (CPE) were 0.99999999999999999999990244 and 0.99999995645, respectively. Furthermore, we explored the genetic relationships between the Ili Uyghur population and 32 previously published populations. The results indicated that the Ili Uyghur population was more closely related to the Xinjiang Kazakh population. In addition, It was worth noting that significant differences were observed between Ili the Uyghur population and the Uyghur1 and Uyghur2 populations at the shared 15 loci, with significant differences at 7 and 11 loci after Bonferroni adjustment (p = 0.05/495 ≈ 0.00010).

Keywords

Genetic polymorphisms Short tandem repeat Uyghur population Ili 

Notes

Acknowledgments

We thank all of the participants of this study.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

414_2018_1872_MOESM1_ESM.docx (51 kb)
Table S1 (DOCX 51 kb)
414_2018_1872_MOESM2_ESM.xlsx (24 kb)
Table S2 (XLSX 23 kb)
414_2018_1872_MOESM3_ESM.xlsx (20 kb)
Table S3 (XLSX 20 kb)
414_2018_1872_MOESM4_ESM.xlsx (17 kb)
Table S4 (XLSX 17 kb)
414_2018_1872_MOESM5_ESM.docx (408 kb)
ESM 1 (DOCX 407 kb)

References

  1. 1.
    Walsh PS, Metzger DA, Higuchi R (1991) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. BioTechniques 10:8Google Scholar
  2. 2.
    Zhao F, Wu X, Cai G, Xu C The application of Modified-Powerstates software in forensic biostatistics. Chin J Forensic Med 18:297–298Google Scholar
  3. 3.
    Peakall R, Smouse PE (2012) GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research--an update. Bioinformatics 28:2537–2539CrossRefGoogle Scholar
  4. 4.
    Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10:564–567CrossRefGoogle Scholar
  5. 5.
    Kumar S, Stecher G, Tamura K (2016) MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol Biol Evol 33:1870–1874CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Zhenghui Li
    • 1
  • Jian Zhang
    • 2
    • 3
  • Yiwen Zhang
    • 2
    • 3
  • Bin Kang
    • 2
    • 3
  • Wanshui Li
    • 2
    • 3
  • Xingchun Zhao
    • 2
    • 3
  • Ziqing Lin
    • 1
  • Jian Ye
    • 2
    • 3
    Email author
  1. 1.Department of Forensic MedicineCriminal Investigation Police University of ChinaShenyangChina
  2. 2.Institute of Forensic Science, Ministry of Public SecurityBeijingChina
  3. 3.National Engineering Laboratory for Forensic ScienceBeijingChina

Personalised recommendations