International Journal of Legal Medicine

, Volume 133, Issue 4, pp 1029–1032 | Cite as

Development of the Kazakhstan Y-chromosome haplotype reference database: analysis of 27 Y-STR in Kazakh population

  • Maxat ZhabaginEmail author
  • Aliya Sarkytbayeva
  • Inkar Tazhigulova
  • Dauren Yerezhepov
  • Svetlana Li
  • Rakhmetolla Akilzhanov
  • Alibek Yeralinov
  • Zhaxylyk Sabitov
  • Ainur Akilzhanova
Population Data


To improve available databases of forensic interest, all Y-STR haplotypes from Kazakh population were presented in this study. The reference database accumulated almost 3650 samples from academic and citizen science. Additionally, 27 Y-STR from Yfiler Plus System were first analyzed in 300 males from Kazakh (Qazaq) populations residing in Kazakhstan. The data is available in the YHDR under accession numbers YA004316 and YA004322. A total of 270 unique haplotypes were observed. Discrimination capacity was 90%. Obtained Y-STR haplotypes exhibited a high intra-population diversity. Analysis of pairwise genetic distances showed lowest RST values from Uighur and Mongolian populations.


Central Asia Kazakh Y chromosome YHRD Forensic Population genetics STR 



We gratefully acknowledge all sample donors who participated in this study. We thank Nazarbayev University students (Aigul Abilmazhinova, Rassul Khakimov, Azamat Bashabayev, Kamila Issabayeva, Dariya Kassybayeva, Akylzhan Zhaken) for the laboratory assistance. We would like to thank Maxim Solomadin and Ayken Askapuli for contributions to this work.


Conceived and designed the experiments: MZ, AA; performed the experiments: AS, IT, DE, SL, AE; analyzed the data: MZ, AS; contributed reagents/materials/analysis tools: AR, AA, SL, AE, IT; wrote the paper: MZ; AS, AA participated in the drafting; study initiation: MZ; read and approved the final version of the paper: all coauthors.

Funding information

This study received primary support from the Ministry of Education and Science of the Republic of Kazakhstan (Grant No. AP05134955).

Compliance with ethical standards

Competing interests

The authors declare that they have no competing interests.

Supplementary material

414_2018_1859_MOESM1_ESM.pdf (5 kb)
Fig S1 (PDF 4.80 kb)
414_2018_1859_MOESM2_ESM.xlsx (783 kb)
ESM 1 (XLSX 782 kb)


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Maxat Zhabagin
    • 1
    Email author
  • Aliya Sarkytbayeva
    • 1
  • Inkar Tazhigulova
    • 2
  • Dauren Yerezhepov
    • 1
  • Svetlana Li
    • 2
  • Rakhmetolla Akilzhanov
    • 3
  • Alibek Yeralinov
    • 4
  • Zhaxylyk Sabitov
    • 5
  • Ainur Akilzhanova
    • 1
  1. 1.National Laboratory AstanaNazarbayev UniversityAstanaRepublic of Kazakhstan
  2. 2.Сentre of Forensic Expertise of the Ministry of Justice of the Republic of KazakhstanAstanaKazakhstan
  3. 3.S.Toraighyrov Pavlodar State UniversityPavlodarRepublic of Kazakhstan
  4. 4.Ministry of Internal Affairs of the Republic of KazakhstanAstanaKazakhstan
  5. 5.L.N.Gumilyov Eurasian National UniversityAstanaRepublic of Kazakhstan

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