Allele frequencies and forensic genetic parameters of 10 supplementary and two CODIS loci in a Japanese population genotyped using an Investigator HDplex Kit

  • Shota Inokuchi
  • Hiroaki Nakanishi
  • Kazuma Nishimura
  • Kazuyuki Saito
Population Data

Abstract

A total of 344 unrelated Japanese adults were genotyped to determine allele frequencies and evaluate forensic parameters for 10 autosomal supplementary non-CODIS loci and 2 autosomal CODIS loci using an Investigator® HDplex Kit for complex relationship testing.

Keywords

Allele frequency Japanese population Investigator® HDplex kit Non-CODIS 

Notes

Compliance with ethical standards

All procedures performed in the study involving human participants were in accordance with the ethical standards of Juntendo University and with the 1964 Helsinki declaration and its later amendments. Informed consent was obtained from all individual participants included in the study.

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

414_2018_1844_MOESM1_ESM.docx (34 kb)
ESM 1 (DOCX 34 kb)
414_2018_1844_MOESM2_ESM.xlsx (13 kb)
ESM 2 (XLSX 13.2 kb)
414_2018_1844_MOESM3_ESM.pptx (397 kb)
ESM 3 Reproducible rare peaks (artifacts) observed at plus stutter positions at the D10S2325 locus analyzed using the Investigator HDplex kit. Reproducible rare peaks are observed in 3 out of 344 samples. (PPTX 396 kb)
414_2018_1844_MOESM4_ESM.xlsx (13 kb)
ESM 4 (XLSX 12.8 kb)

References

  1. 1.
    Poetsch M, Bajanowski T, Pfeiffer H (2012) The publication of population genetic data in the International Journal of Legal Medicine: guidelines. Int J Legal Med 126:489–490.  https://doi.org/10.1007/s00414-012-0700-z CrossRefGoogle Scholar
  2. 2.
    Rousset F (2008) genepop’007: a complete re-implementation of the genepop software for Windows and Linux. Mol Ecol Resour 8:103–106.  https://doi.org/10.1111/j.1471-8286.2007.01931.x CrossRefPubMedGoogle Scholar
  3. 3.
    Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10:564–567.  https://doi.org/10.1111/j.1755-0998.2010.02847.x CrossRefPubMedGoogle Scholar
  4. 4.
    Jung JY, Kim EH, Oh Y-L, Park HC, Hwang JH, Lim SK (2017) Evaluation of forensic genetic parameters of 12 STR loci in the Korean population using the Investigator® HDplex kit. Int J Legal Med 131:1247–1249.  https://doi.org/10.1007/s00414-017-1592-8 CrossRefPubMedGoogle Scholar
  5. 5.
    Zhang S, Zhang Z, Zhao S, Zhao Z, Li C (2013) Genetic polymorphisms in 12 autosomal STRs in a Shanghai Han population from China. Electrophoresis 34:613–617.  https://doi.org/10.1002/elps.201200423 CrossRefPubMedGoogle Scholar
  6. 6.
    Schmid D, Anslinger K, Rolf B (2005) Allele frequencies of the ACTBP2 (=SE33), D18S51, D8S1132, D12S391, D2S1360, D3S1744, D5S2500, D7S1517, D10S2325 and D21S2055 loci in a German population sample. Forensic Sci Int 151:303–305.  https://doi.org/10.1016/j.forsciint.2005.02.003 CrossRefPubMedGoogle Scholar
  7. 7.
    Tillmar AO, Nilsson H, Kling D, Montelius K (2013) Analysis of Investigator HDplex markers in Swedish and Somali populations. Forensic Sci Int Genet 7:e21–e22.  https://doi.org/10.1016/j.fsigen.2012.08.006 CrossRefPubMedGoogle Scholar
  8. 8.
    Martínez G, Borosky A, Corach D, Llull C, Locarno L, Lojo M, Marino M, Miozzo MC, Modesti N, Pacharoni C, Pilili JP, Ramella MI, Sala A, Schaller C, Vullo C, Toscanini U (2017) Investigator® HDplex (Qiagen) reference population database for forensic use in Argentina. Forensic Sci Int Genet 26:91–95.  https://doi.org/10.1016/j.fsigen.2016.10.009 CrossRefPubMedGoogle Scholar
  9. 9.
    Inokuchi S, Yamashita Y, Nishimura K, Nishimura K, Nakanishi H, Saito K (2017) Identification of a common single nucleotide polymorphism at the primer binding site of D2S1360 that causes heterozygote peak imbalance when using the Investigator HDplex Kit. Int J Legal Med 131:1531–1535.  https://doi.org/10.1007/s00414-017-1571-0

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Forensic Medicine, Graduate School of MedicineJuntendo UniversityTokyoJapan
  2. 2.Forensic Science Laboratory, Tokyo Metropolitan Police DepartmentTokyoJapan

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