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International Journal of Legal Medicine

, Volume 133, Issue 2, pp 427–428 | Cite as

Allele frequencies of 18 autosomal STR loci in the Uyghur population living in Kashgar Prefecture, Northwest China

  • Jian Zhang
  • Zhenghui Li
  • Xiaoting Mo
  • Wenhua Ma
  • Hantao Zhang
  • Ziqing Lin
  • Jian YeEmail author
Population Data

Abstract

There is currently no large population data-based data set in Kashgar Prefecture Uyghur. The allele frequencies of 18 autosomal short tandem repeat (STR) loci included in the DNATyper™ 19 kit were evaluated in 2600 Uyghur individuals living in Kashgar Prefecture, Northwest China. The values of combined power of discrimination (CPD) and combined probability of exclusion (CPE) of all 18 autosomal STR loci were 0.99999999999999999998235 and 0.99999998670, respectively. Phylogenetic analyses revealed that the Uyghur population has a closer relationship with the Xinjiang-Kazakh, Inner Mongolia-Mongolian, and other three Uyghur populations. In addition, our results are consistent with the hypothesis that Uyghur population is an admixture of Eastern Asian and European populations.

Keywords

Short tandem repeat (STR) Population data Uyghur population Kashgar Prefecture 

Notes

Acknowledgments

We thank all of the participants in this study.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

414_2018_1821_MOESM1_ESM.docx (522 kb)
ESM 1 (DOCX 522 kb)
414_2018_1821_MOESM2_ESM.xlsx (40 kb)
ESM 2 (XLSX 40 kb)

References

  1. 1.
    Xu S, Huang W, Qian J, Jin L (2008) Analysis of genomic admixture in Uyghur and its implication in mapping strategy. Am J Hum Genet 82(4):883–894CrossRefGoogle Scholar
  2. 2.
    Zhao F, Wu X, Cai G, Xu C (2003) The application of modified-Powerstates software in forensic biostatistics. Chin J Forensic Med 18:297–298Google Scholar
  3. 3.
    Peakall R, Smouse PE (2012) GenAlEx 6.5: genetic analysis in excel. Population genetic software for teaching and research—an update. Bioinformatics 28(19):2537–2539CrossRefGoogle Scholar
  4. 4.
    Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10(3):564–567CrossRefGoogle Scholar
  5. 5.
    Kumar S, Stecher G, Tamura K (2016) MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol Biol Evol 33(7):1870–1874CrossRefGoogle Scholar
  6. 6.
    Li Z, Zhang J, Zhang H, Lin Z, Ye J (2017) Genetic polymorphisms in 18 autosomal STR loci in the Tibetan population living in Tibet Chamdo, Southwest China. Int J Legal MedGoogle Scholar
  7. 7.
    Zhang X, Hu L, Du L, Nie A, Rao M, Pang JB, Xiran Z, Nie S (2017) Genetic analysis of 20 autosomal STR loci in the Miao ethnic group from Yunnan Province, Southwest China. Forensic Sci Int Genet 28:e28-e29Google Scholar
  8. 8.
    Bindu GH, Trivedi R, Kashyap VK (2007) Allele frequency distribution based on 17 STR markers in three major Dravidian linguistic populations of Andhra Pradesh, India. Forensic Sci Int 170(1):76–85CrossRefGoogle Scholar
  9. 9.
    Di Cristofaro J, Buhler S, Temori SA, Chiaroni J (2012) Genetic data of 15 STR loci in five populations from Afghanistan. Forensic Sci Int Genet 6(1):e44–e45CrossRefGoogle Scholar
  10. 10.
    Yuan L, Liu H, Liao Q, Xu X, Chen W, Hao S (2016) Genetics analysis of 38 STR loci in Uygur population from Southern Xinjiang of China. Int J Legal Med 130(3):687–688CrossRefGoogle Scholar
  11. 11.
    He GL, Chen PY, Gao B, Han YY, Zou X, Song F, Yan J, Hou YP (2017) Phylogenetic analysis among 27 Chinese populations and genetic polymorphisms of 20 autosomal STR loci in a Chinese Uyghur ethnic minority group. Aust J Forensic Sci:1–10Google Scholar
  12. 12.
    Zhang L, Xu C, Chen H, Zhou Y, Li F, Chen J (2012) Genetic polymorphism of 19 STR loci in Kazakh population living in Barkol. Xinjiang J Cent South Univ (Med Sci) 37(9):934–938Google Scholar
  13. 13.
    Bian Y, Zhang S, Zhou W, Zhao Q, Siqintuya ZR, Wang Z, Gao Y, Hong J, Lu D, Li C (2016) Analysis of genetic admixture in Uyghur using the 26 Y-STR loci system. Sci Rep 6:19998CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Jian Zhang
    • 1
    • 2
  • Zhenghui Li
    • 3
  • Xiaoting Mo
    • 1
    • 2
  • Wenhua Ma
    • 1
    • 2
  • Hantao Zhang
    • 3
  • Ziqing Lin
    • 3
  • Jian Ye
    • 1
    • 2
    Email author
  1. 1.Institute of Forensic ScienceMinistry of public securityBeijingChina
  2. 2.National Engineering Laboratory for Forensic ScienceBeijingChina
  3. 3.Department of Forensic MedicineCriminal Investigation Police University of ChinaShenyangChina

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