The association of allergic rhinitis severity with neutrophil–lymphocyte and platelet–lymphocyte ratio in adults
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To investigate the association of allergic rhinitis (AR) severity with neutrophil–lymphocyte and platelet–lymphocyte ratios in adult patients.
The study design was prospective observational study and the study included 209 AR patients and 243 healthy individuals. The patient group comprised 38.2% males with a mean age of 31.8 years. All patients who were diagnosed with persistent AR were included. The healthy control group comprised 52.7% males with a mean age of 32.3 years. The blood examination results of patients and healthy individuals were compared in terms of neutrophil–lymphocyte and platelet–lymphocyte ratios. The values were further compared within the patient group, according to AR severity.
The neutrophil–lymphocyte ratio was 1.70 ± 0.65 in the healthy group and 2.02 ± 1.24 in the patient group. The platelet–lymphocyte ratio result was 100.85 ± 25.33 in the healthy group and 120.67 ± 40.59 in the patient group. When we compared the neutrophil–lymphocyte and platelet–lymphocyte ratios between the groups, we found statistically significant differences in both ratios (p = 0.003, p = 0.000, respectively). Both the neutrophil–lymphocyte and the platelet–lymphocyte ratios were higher in patients with moderate–severe AR.
Both neutrophil–lymphocyte and platelet–lymphocyte ratios are useful markers for diagnosis of persistent AR. Specialists may benefit from these markers to assess the severity of the disease at the beginning of the diagnostic process.
KeywordsAllergic rhinitis Neutrophil–lymphocyte ratio Platelet–lymphocyte ratio
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
The study design was prospective observational study and this research was performed with human participants. All patients were signed written informed consent.
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