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European Archives of Oto-Rhino-Laryngology

, Volume 276, Issue 11, pp 3159–3164 | Cite as

Three-dimensional imaging of vocalizing larynx by ultra-high-resolution computed tomography

  • Makoto Miyamoto
  • Arisa Ohara
  • Takahiro Arai
  • Masamichi Koyanagi
  • Itaru Watanabe
  • Hideki Nakagawa
  • Kenichi Yokoyama
  • Koichiro SaitoEmail author
Laryngology

Abstract

Purpose

Ultra-high-resolution computed tomography (UHRCT) is an emerging imaging technology that is able to achieve simultaneous 160 slices with super-thin 0.25 mm thickness. The purpose of this study was to assess the feasibility of UHRCT to visualize laryngeal structure and kinetics.

Methods

Three normal volunteers and three patients with unilateral vocal fold paralysis (UVFP) were incorporated in this case series. First, images were taken under five conditions in normal volunteers. Five tasks consisted of (1) air inspiration through the nose (IN), (2) breath holding (BH), (3) sustained vowel /i:/ phonation (IP), (4) humming phonation (HP), and (5) forced glottic closure during exhalation (FC). Three-dimensional CT images of arytenoid and cricoid cartilages, as well as virtual laryngoscopic images, were reconstructed using UHRCT data. Reconstructed images were compared among five conditions to assess the best tasks to picture laryngeal kinetics. Second, pre- and post-phonosurgical images were examined in UVFP patients to evaluate potential role of UHRCT to assess laryngeal pathology in hoarse patients.

Results

Among the five conditions, IN and IP conditions were considered suitable to visualize laryngeal structure at rest and during phonation, respectively. Kinetic abnormalities including asymmetric motion of arytenoid cartilages were elucidated in UVFP patients, and virtual endoscopy visualized the clinically invisible posterior three-dimensional glottic chinks. Furthermore, UHRCT was useful to understand changes in laryngeal structure achieved by phonosurgery.

Conclusions

UHRCT is an emerging imaging technology that can be used for minimally invasive visualization and assessment of laryngeal structure and kinetics. Future studies to assess more number of patients with laryngeal dysfunction are warranted.

Keywords

Ultra-high-resolution computed tomography Unilateral vocal fold paralysis Laryngeal imaging Virtual endoscopy Three-dimensional reconstruction 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Otolaryngology-Head and Neck SurgeryKyorin University School of MedicineTokyoJapan
  2. 2.Department of RadiologyKyorin University School of MedicineTokyoJapan

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