Response to the Letter to the Editor: “Pediatric otogenic lateral sinus thrombosis: focus on the prognostic role of contralateral venous drainage”

  • Alessandro ScorpecciEmail author
  • Pasquale Marsella
  • Sara Giannantonio
  • Paola Zangari
  • Daniela Longo
  • Matteo Luciani
Letter to the Editor

We appreciate the interest in our study. The Letter titled “Pediatric otogenic lateral sinus thrombosis: focus on the prognostic role of contralateral venous drainage” raises several points concerning the most appropriate neuroimaging technique for diagnosis, the role of contralateral venous drainage and the indication to surgical treatment and anticoagulant therapy.

With regard to the neuroimaging technique, the authors of the letter state that contrast-enhanced MRI and angio-MRI with a venous phase of contrast-enhancement should be the rule. Most of the cases described in our 11-year retrospective review were diagnosed with CT scan with contrast when they came to clinical attention in the emergency department of our hospital, for the simple reason that CT scan is much easier to be obtained than MRI, which often requires general anesthesia in children. A joint statement by the American Heart Association and the American Stroke Association [1] recommends that CT-venography or...




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Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Saposnik G, Barinagarrementeria F, Brown RD Jr, Bushnell CD, Cucchiara B, Cushman M, deVeber G, Ferro JM, Tsai FY, American Heart Association Stroke Council and the Council on Epidemiology and Prevention (2011) Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 42(4):1158–1192CrossRefGoogle Scholar
  2. 2.
    Scorpecci A, Massoud M, Giannantonio S, Zangari P, Lucidi D, Martines F, Foligno S, Di Felice G, Minozzi A, Luciani M, Marsella P (2018) Otogenic lateral sinus thrombosis in children: proposal of an experience-based treatment flowchart. Eur Arch Otorhinolaryngol 275(8):1971–1977CrossRefGoogle Scholar
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    Chalmers E, Ganesen V, Liesner R, Maroo S, Nokes T, Saunders D, Williams M, British Committee for Standards in Haematology (2011) Guideline on the investigation, management and prevention of venous thrombosis in children. Br J Haematol 154(2):196–207CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Audiology and Otosurgery Unit, Department of Surgery, Cochlear Implant Referral Center“Bambino Gesù” Pediatric HospitalRomeItaly
  2. 2.Haemostasis and Thrombosis Center, Oncohematology DepartmentBambino Gesù Pediatric HospitalRomeItaly
  3. 3.Neuroradiology Unit, Imaging DepartmentBambino Gesù Children’s HospitalRomeItaly

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