Outcomes of salvage surgery for the oropharynx and larynx: a contemporary experience in a UK Cancer Centre
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The purpose of this study was to review our recent experience of salvage surgery, comparing larynx and oropharynx recurrence patterns.
A single centre, retrospective review of salvage surgery for recurrent head and neck cancer including patients between 2008 and 2016.
61 patients were identified, 36 underwent salvage laryngectomy and 25 received oropharyngeal resections. The median overall survival of oropharyngeal recurrent tumors was 26 months (95% CI 15–118 months) and for laryngeal tumors was 23 months (95% CI 11–38 months), p = 0.1008. There was a significant overall survival benefit in patients with negative resection margin. The median survival in the negative margin group was 38 months (95% CI 25–108 months) compared to the positive margin group, 9 months (95% CI 5–15 months), p < 0.0001.
Survival results following surgical salvage in the larynx and oropharynx appear to be similarly poor. Those patients with clear margins appear to have a significantly better prognosis.
KeywordsOropharynx cancer Larynx cancer Salvage surgery Recurrent head and neck cancer
This study was not funded.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
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