European Archives of Oto-Rhino-Laryngology

, Volume 276, Issue 1, pp 223–231 | Cite as

Impact of age on elderly patients with oral cancer

  • Akshat Malik
  • Aseem Mishra
  • Prashant Chopda
  • Hitesh Singhvi
  • Sudhir Nair
  • Deepa Nair
  • Sarbani Ghosh Laskar
  • Kumar Prabhash
  • Jai Prakash Agarwal
  • Pankaj ChaturvediEmail author
Head & Neck



In this study we have tried to analyze the impact of age on various clinico-pathological parameters, treatment completion and subsequent survival in older patients.

Materials and methods

This is a retrospective analysis of 140 elderly (> 65 years) patients of oral cancer operated between January 2012 and December 2013. The patients were divided into two groups based upon their age that ≤ 70 years and > 70 years.Association of distribution of various clinico-pathological factors between different groups was assessed by using Chi-square test. Survival analysis was done using Kaplan Meir analysis. Univariate and multivariate analysis were performed.


The two groups had similar distribution of various clinico-pathological factors. Disease free survival for the group ≤ 70 and > 70 years was 37.6 months and 36.4 months (p < 0.594). 13.5% and 7.8% patients > 70 years and ≤ 70 years were either advised or received sub-optimal adjuvant therapy (p < 0.002).


There is no difference distribution of various clinico-pathological factors and survival in patients of oral cancer ≤ 70 and > 70 years of age. Age did not affect survival. Majority of patients could complete the adjuvant therapy advised. Still, significantly more number of patients > 70 years could not receive/complete appropriate adjuvant therapy. Thus treatment needs to be tailored keeping in mind the individual’s performance status and the co-morbidities.


Oral cancer Geriatric patients Survival Age Adjuvant therapy 






Compliance with ethical standards

Conflict of interest

The authors declare that there is no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Akshat Malik
    • 1
  • Aseem Mishra
    • 1
  • Prashant Chopda
    • 1
  • Hitesh Singhvi
    • 1
  • Sudhir Nair
    • 1
  • Deepa Nair
    • 1
  • Sarbani Ghosh Laskar
    • 2
  • Kumar Prabhash
    • 3
  • Jai Prakash Agarwal
    • 2
  • Pankaj Chaturvedi
    • 1
    Email author
  1. 1.Department of Head and Neck OncologyTata Memorial CentreMumbaiIndia
  2. 2.Department of Radiation OncologyTata Memorial CentreMumbaiIndia
  3. 3.Department of Medical OncologyTata Memorial CentreMumbaiIndia

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