European Archives of Oto-Rhino-Laryngology

, Volume 276, Issue 1, pp 273–273 | Cite as

Electrolyte balance and voice in hemodialysis patients

  • Beuy JoobEmail author
  • Viroj Wiwanitkit
Letter to the Editor

Dear Editor,

We read the publication on “The effect of electrolyte balance on the voice in hemodialysis patients” with a great interest [1]. Sagiroglu and Doganer noted that “uric acid was the agent creating a reduction in vocal cord vibration, the agent increasing the difference between vibration waves was Na+, and creatinine increased the NHR rate [1].” Indeed, there are other possible factors that might affect the voice in hemodialysis. As a stressful event, the inflammation might occur according to the dialysis [2]. To rule out the concurrent effect of possible hidden inflammation, the erythrocyte sedimentation rate (ESR) might be additional used as a control parameter in the present study. Finally, the problem of laboratory interference on measurement of uric acid in the patients with dialysis should be mentioned [3]. If the colorimetric test is used for measurement of uric acid, the error can be expected in cases undergoing dialysis [3]. In addition, the concurrent use of some common drugs such as acetaminophen also result in aberrant serum uric acid result in hemodialysis patient [4].


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Sagiroglu S, Doganer A (2018) The effect of electrolyte balance on the voice in hemodialysis patients. Eur Arch Otorhinolaryngol. (epub ahead of print) Google Scholar
  2. 2.
    Borawski J, Myśliwiec M (2001) The hematocrit-corrected erythrocyte sedimentation rate can be useful in diagnosing inflammation in hemodialysis patients. Nephron 89(4):381–383CrossRefGoogle Scholar
  3. 3.
    James DR, Price CP (1984) Interference in colorimetric reactions for measuring hydrogen peroxide. Ann Clin Biochem 21(Pt 5):398–404CrossRefGoogle Scholar
  4. 4.
    Tanner R, Arund J, Fridolin I, Luman M (2013) Paracetamol interference in uric acid levels in uremic patients revealed by monitoring spent dialysate. ISRN Nephrol 1:515292Google Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Sanitation 1 Medical Academic CenterBangkokThailand
  2. 2.Dr. D. Y. Patil UniversityPuneIndia

Personalised recommendations