Correlation between fetal Doppler indices and neonatal acid–base status at birth in healthy appropriate for gestational age term fetuses

  • Nicola Fratelli
  • Valentina Benedetta Brunelli
  • Vera Gerosa
  • Enrico Sartori
  • Andrea Lojacono
  • Federico PrefumoEmail author

Dear Sir,

Recent evidence published in this journal [ 1] and by our group [ 2] does not entirely clarify whether fetal cerebroplacental ratio (CPR) measured shortly before labour could identify fetuses likely to require obstetric intervention for intrapartum fetal compromise. In fact, the use of Cesarean section for fetal distress and composite adverse neonatal outcome as surrogate markers of prelabor fetal hypoxia does not allow to understand if CPR is a good predictor of antepartum fetal oxygenation, or if events in labor play a greater role than prelabor fetal oxygenation in the development of intrapartum fetal distress [ 1, 2, 3, 4]. Aiming to clarify this issue, we performed a prospective observational cohort study in healthy, appropriate for gestational age (AGA) term fetuses to evaluate the correlation between maternal/fetal Doppler waveforms and umbilical cord acid–base analysis, the most objective assessment of the acid–base status at birth. We included 48 singleton pregnancies...


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Conflict of interest

The authors have no conflict of interest to declare.


  1. 1.
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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Division of Obstetrics and Gynecology, Department of Clinical and Experimental SciencesASST Spedali Civili and University of BresciaBresciaItaly

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