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Archives of Gynecology and Obstetrics

, Volume 289, Issue 6, pp 1235–1239 | Cite as

Differences in the clinical phenotype of adenomyosis and leiomyomas: a retrospective, questionnaire-based study

  • Bettina Boeer
  • Markus Wallwiener
  • Joachim Rom
  • Birgitt Schoenfisch
  • Sara Y. Brucker
  • Florin A. TaranEmail author
General Gynecology

Abstract

Purpose

To compare women undergoing laparoscopic hysterectomy with adenomyosis and women with leiomyomas.

Materials and methods

Retrospective and questionnaire-based study was conducted at the Department of Obstetrics and Gynecology, University Women’s Clinic, Tuebingen, Germany. The study sample comprised a total of 454 women who underwent hysterectomy for adenomyosis or leiomyomas and responded to the questionnaire; 52 (11.4 %) women with a histologic diagnosis of adenomyosis and 452 (88.6 %) women with a histologic diagnosis of leiomyomas.

Results

Both groups of patients had enlarged uteri, but women with adenomyosis had a lower mean uterine weight as compared to women with leiomyomas (p < 0.001). Women with adenomyosis had significantly more pregnancies (p = 0.003), were more likely to have more than one pregnancy (p = 0.033) or more than one delivery (p = 0.025) as compared to women with leiomyomas. In addition, women with adenomyosis had a significantly higher surgical procedure score (p = 0.017), had more frequently a history of laparotomy (p = 0.042) and a history of Cesarean section as compared to women with leiomyomas only (p = 0.024). Significantly, more women with adenomyosis had pelvic pain or pressure as compared to women with leiomyomas (p = 0.045). We observed no differences between the two groups of patients regarding pelvic pain during the menstrual period, irregular menstrual periods, heavy bleeding, painful sexual intercourse and urination problems. Furthermore, we observed no differences in the therapeutic impact of the surgical procedure between the two patient groups.

Conclusions

Women with a histologic diagnosis of adenomyosis differ from women who have only leiomyomas at the time of hysterectomy.

Keywords

Adenomyosis Leiomyomas 

Notes

Conflict of interest

We declare that we have no conflict of interest.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Bettina Boeer
    • 1
  • Markus Wallwiener
    • 2
  • Joachim Rom
    • 2
  • Birgitt Schoenfisch
    • 1
  • Sara Y. Brucker
    • 1
  • Florin A. Taran
    • 1
    Email author
  1. 1.Department of Obstetrics and GynecologyUniversity Women’s ClinicTuebingenGermany
  2. 2.Department of Obstetrics and GynecologyUniversity Women’s ClinicHeidelbergGermany

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