Abstract
Dermoscopy can be used in diagnosis of some chronic inflammatory dermatoses. In this study, the single most recent, fully developed lesion in 74 patients with clinically inflammatory dermatoses was examined dermoscopically and correlated histopathologically with psoriasiform, lichenoid, or spongiotic reaction patterns. Vascular component (morphology and arrangement) was the most prominent feature in the studied patterns mostly in the shape of dots (45 specimens, 60.8 %), globules (30 specimens, 40.5 %), and lines (45 specimens, 60.8 %). Psoriasiform pattern showed vascular dots (20 specimens, 76.92 %), and/or red globules (15 specimen, 57.69 %), regularly distributed (17 specimens, 65.38 %), on intense red background (15 specimens, 57.69 %), and diffuse (13 specimens, 50 %) white scales (18 specimen, 69.23 %), with probability of these features together 100 %. Lichenoid pattern showed red lines (23 cases, 65.71 %), on dull or light red background (14 cases, 40 % for each), with discolored areas (15 cases, 42.86 %), brown reticular pigmentation (21 cases, 60 %), and white scales (13 cases, 37.14 %). Spongiotic pattern was characterized by follicular component and diffuse or peripheral scale distribution, with probability of both features together 100 %. The main histopathologic features of inflammatory dermatoses, which influenced their dermoscopic patterns, are depth and size of vessels, presence and shape of epidermal hyperplasia, presence of spongiosis, and degree of dermal inflammation and oedema. These features influenced vascular morphology and distribution, corneal component, and background color. Among the studied reaction patterns, psoriasiform pattern showed the most consistent correlation with dermoscopic features. Dermoscopic picture of lichenoid reaction was the most contradictory. Spongiotic reaction showed absent specific vascular component.
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Abbreviations
- CLE:
-
Chronic lupus erythematosus
- LP:
-
Lichen planus
- p :
-
Probability factor
- PP:
-
Plaque psoriasis
- SD:
-
Seborrhoeic dermatitis
- SPSS:
-
Statistical program for social science
References
Ackerman AB (1978) Histologic diagnosis of inflammatory skin diseases A method by pattern analysis. Lea & Febiger, Philadelphia 437
Ackerman AB (1985) An algorithmic method for histologic diagnosis of inflammatory and neoplastic skin diseases by analysis of their patterns. Am J Dermatopathol 7:105–107
Fox BJ, Odom RB (1985) Papulosquamous diseases: a review. J Am Acad Dermatol 12:597–624
Lallas A, Giacomel J, Argenziano G, García-García B, González-Fernández D, Zalaudek I, Vázquez-López F (2014) Dermoscopy in General Dermatology: Practical Tips for the Clinician. Br J Dermatol 170(3):514–526
Lallas A, Kyrgidis A, Tzellos TG, Apalla Z, Karakyriou E, Karatolias A, Lefaki I, Sotiriou E, Ioannides D, Argenziano G, Zalaudek I (2012) Accuracy of dermoscopic criteria for the diagnosis of psoriasis, dermatitis, lichen Planus and pityriasis rosea. Br J Dermatol 166:1198–1205
Malvehy J, Puig S, Braun RP, Marghoob AA, Kopf AW (2006) Handbook of dermoscopy. Taylor & Francis, London, pp 88–90
Tirumalae Rajalakshmi (2013) Psoriasiform Dermatoses: microscopic approach. Indian J Dermatol 58(4):290–293
Souid K (2011) Diagnostic differential des dermatoses inflammatoires: place de la dermatoscopie. Ann Dermatol Venereol 138:141–142
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Goncharova, Y., Attia, E.A.S., Souid, K. et al. Dermoscopic features of clinically inflammatory dermatoses and their correlation with histopathologic reaction patterns. Arch Dermatol Res 307, 23–30 (2015). https://doi.org/10.1007/s00403-014-1513-3
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DOI: https://doi.org/10.1007/s00403-014-1513-3