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Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile

  • David A. Solomon
  • Andrey Korshunov
  • Martin Sill
  • David T. W. Jones
  • Marcel Kool
  • Stefan M. Pfister
  • Xuemo Fan
  • Serguei Bannykh
  • Jethro Hu
  • Moise Danielpour
  • Rong Li
  • James Johnston
  • Elaine Cham
  • Tabitha Cooney
  • Peter P. Sun
  • Nancy Ann Oberheim Bush
  • Michael McDermott
  • Jessica Van Ziffle
  • Courtney Onodera
  • James P. Grenert
  • Boris C. Bastian
  • Javier E. Villanueva-Meyer
  • Melike Pekmezci
  • Andrew W. Bollen
  • Arie Perry
Correspondence

Notes

Acknowledgements

D.A.S. is supported by NIH Director’s Early Independence Award (DP5 OD021403) and the UCSF Physician-Scientist Scholar Program. B.C.B. is supported by an NCI Outstanding Investigator Award (R35 CA220481).

Compliance with ethical standards

This study was approved by the Committee on Human Research of the University of California, San Francisco, with a waiver of patient consent.

Conflict of interest

The authors declare that they have no competing interests related to this study.

Supplementary material

401_2018_1883_MOESM1_ESM.xlsx (26 kb)
Supplementary material 1 (XLSX 26 kb)
401_2018_1883_MOESM2_ESM.pdf (15.7 mb)
Supplementary material 2 (PDF 16038 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • David A. Solomon
    • 1
    • 2
  • Andrey Korshunov
    • 3
    • 4
  • Martin Sill
    • 5
    • 6
    • 7
  • David T. W. Jones
    • 5
    • 6
  • Marcel Kool
    • 5
    • 6
  • Stefan M. Pfister
    • 5
    • 6
    • 7
  • Xuemo Fan
    • 8
  • Serguei Bannykh
    • 8
  • Jethro Hu
    • 9
  • Moise Danielpour
    • 10
  • Rong Li
    • 11
  • James Johnston
    • 12
  • Elaine Cham
    • 13
  • Tabitha Cooney
    • 14
  • Peter P. Sun
    • 15
  • Nancy Ann Oberheim Bush
    • 16
  • Michael McDermott
    • 17
  • Jessica Van Ziffle
    • 1
    • 2
  • Courtney Onodera
    • 1
    • 2
  • James P. Grenert
    • 1
    • 2
  • Boris C. Bastian
    • 1
    • 2
  • Javier E. Villanueva-Meyer
    • 18
  • Melike Pekmezci
    • 1
  • Andrew W. Bollen
    • 1
  • Arie Perry
    • 1
    • 17
  1. 1.Department of PathologyUniversity of CaliforniaSan FranciscoUSA
  2. 2.Clinical Cancer Genomics LaboratoryUniversity of CaliforniaSan FranciscoUSA
  3. 3.Department of NeuropathologyHeidelberg University HospitalHeidelbergGermany
  4. 4.Clinical Cooperation Unit NeuropathologyGerman Cancer Research Center (DKFZ)HeidelbergGermany
  5. 5.Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ)HeidelbergGermany
  6. 6.Division of Pediatric Neuro-OncologyGerman Cancer Consortium (DKTK), German Cancer Research Center (DKFZ)HeidelbergGermany
  7. 7.Department of Pediatric Hematology and OncologyHeidelberg University HospitalHeidelbergGermany
  8. 8.Department of PathologyCedars Sinai Medical CenterLos AngelesUSA
  9. 9.Department of NeurologyCedars Sinai Medical CenterLos AngelesUSA
  10. 10.Department of NeurosurgeryCedars Sinai Medical CenterLos AngelesUSA
  11. 11.Department of PathologyChildren’s Hospital of AlabamaBirminghamUSA
  12. 12.Department of NeurosurgeryChildren’s Hospital of AlabamaBirminghamUSA
  13. 13.Department of PathologyUCSF Benioff Children’s Hospital OaklandOaklandUSA
  14. 14.Department of Hematology/OncologyUCSF Benioff Children’s Hospital OaklandOaklandUSA
  15. 15.Department of Neurological SurgeryUCSF Benioff Children’s Hospital OaklandOaklandUSA
  16. 16.Division of Neuro-Oncology, Department of Neurological SurgeryUniversity of CaliforniaSan FranciscoUSA
  17. 17.Department of Neurological SurgeryUniversity of CaliforniaSan FranciscoUSA
  18. 18.Department of Radiology and Biomedical ImagingUniversity of CaliforniaSan FranciscoUSA

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