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How to maximize QRS narrowing

  • Olivia Braun
  • Mate Vamos
  • Julia W. Erath
  • Stefan H. HohnloserEmail author
Case Reports
  • 23 Downloads

Abstract

Background

Cardiac resynchronization therapy (CRT) resulting in maximal QRS narrowing may be associated with improved outcomes.

Methods

Various atrioventricular (AV) delay settings, including the new SyncAV™ algorithm (St. Jude Medical/Abbott, St. Paul, MN, USA), aimed at maximal QRS narrowing were tested in an 81-year old CRT recipient.

Results

Maximal QRS narrowing from 160 to 100 ms was achieved with a manually programmed value of SyncAV™ −30 ms. At 2 months, the patient proved to be a CRT super-responder.

Conclusion

SyncAV™ algorithm is a new way for effective QRS narrowing with potentially improved outcomes.

Keywords

Cardiac resynchronization therapy Multipoint pacing QRS narrowing AV delay SyncAV™ 

Abbreviations

AV

Atrioventricular

BiV

Biventricular

CRT

Cardiac resynchronization therapy

CRT-P

Cardiac resynchronization therapy pacemaker

LV

Left ventricle

LVEF

Left ventricular ejection fraction

LVEDD

Left ventricle end diastolic diameter

LVESD

Left ventricle end systolic diameter

LVESV

Left ventricle end systolic volume

MPP

Multipoint pacing

NYHA

New York Heart Association

RV

Right ventricle

VV

Ventriculoventricular

Methode zur Maximierung der QRS-Verschmälerung

Zusammenfassung

Hintergrund

Eine kardiale Resynchronisationstherapie (CRT) mit maximaler Verkürzung der QRS-Dauer kann mit besseren Behandlungsergebnissen einhergehen.

Methoden

Diverse Programmierungen der atrioventrikulären (AV) Zeit, inklusive des neuen SyncAV™-Algorithmus (St. Jude Medical/Abbott, St. Paul, MN, USA), wurden bei einem 81-jährigen Patienten mit CRT zur Verschmälerung des QRS-Komplexes getestet.

Ergebnisse

Die maximale Verschmälerung des QRS-Komplexes von 160 auf 100 ms wurde mittels individueller SyncAV™-Programmierung auf −30 ms erreicht. Nach 2 Monaten erwies sich der Patient als „CRT-Super-Responder“.

Schlussfolgerung

Der SyncAV™-Algorithmus stellt eine neue Methode zur effektiven Verkürzung der QRS-Dauer dar und kann potenziell zu einer Prognoseverbesserung beitragen.

Schlüsselwörter

Kardiale Resynchronisationstherapie Multipoint-Stimulation Verschmälerung des QRS-Komplexes AV-Verzögerung SyncAV™ 

Notes

Compliance with ethical guidelines

Conflict of interest

O. Braun, M. Vamos, J.W. Erath and S.H. Hohnloser declare that they have no competing interests.

For this article no studies with human participants or animals were performed by any of the authors. All studies performed were in accordance with the ethical standards indicated in each case. Additional written informed consent was obtained from all individual participants or their legal representatives for whom identifying information is included in this article.

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Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2019

Authors and Affiliations

  • Olivia Braun
    • 1
  • Mate Vamos
    • 1
  • Julia W. Erath
    • 1
  • Stefan H. Hohnloser
    • 2
    Email author
  1. 1.University Hospital FrankfurtGoethe University FrankfurtFrankfurtGermany
  2. 2.Department of Cardiology, Division of Clinical Electrophysiology, University Hospital FrankfurtGoethe University FrankfurtFrankfurt am MainGermany

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