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International Journal of Colorectal Disease

, Volume 34, Issue 11, pp 1879–1885 | Cite as

Colon cancer in the young: contributing factors and short-term surgical outcomes

  • Kamil Hanna
  • Muhammad Zeeshan
  • Mohammad Hamidi
  • Viraj Pandit
  • Pamela Omesiete
  • Alejandro Cruz
  • Agnes Ewongwo
  • Bellal Joseph
  • Valentine NfonsamEmail author
Original Article
  • 124 Downloads

Abstract

Background

The incidence in young patients has increased significantly over the last few decades. The aim of this study is to evaluate demographic and tumor characteristics of young patients and analyze the short-term surgical outcomes of patients undergoing surgery.

Methods

We performed a 2-year review (2015–2016) of the ACS-NSQIP and included all patients with CC who underwent surgical management. Patients were stratified into two groups: early-onset CC (< 50 years old) and late-onset CC (≥ 50 years old). Outcome measures were hospital length of stay, 30-day complications, mortality, and readmission.

Results

We included a total of 15,957 patients in the analysis. Mean age was 65 ± 13 years, and 52% were male. Overall 10% of the patients had early-onset CC. Patients with early-onset CC were more likely to be black (11% vs 7%, p = 0.04) and Hispanic (8% vs 4%, p = 0.02). Additionally, they presented with a more aggressive tumor and higher TNM staging. Patients with early onset CC had lower 30-day complications (18% vs 22%, p = 0.02), shorter hospital length of stay (6[3–8] vs 8[5–11], p = 0.03) and lower 30-day mortality (0.4% vs 1.8%, p = 0.04) compared to their counterparts. However, there was no difference between the two groups regarding 30-day readmission. On regression analysis, there was no difference between the two groups regarding study outcomes.

Conclusions

Racial disparity does exist in the incidence of colon cancer in the young with higher incidence in blacks. Younger patients with CC tend to have better surgical outcomes on univariate analysis. On regression analysis, the surgical outcomes between the two groups are comparable.

Keywords

Colon cancer Young patients Nationwide Surgical Quality Improvement Program Racial disparities Ethnic disparities 

Notes

Author contributions

Study design and conception: VN, MH, MZ, KH, AE.

Data acquisition: AC, VN, KH, MH, PO, BJ, VP.

Statistical analysis: PO, VN, KH, MH, VP.

Manuscript writing: MZ, AE, MH, KH, VN, BJ, VP.

Critical revision: AC, VN, KH, MH, MZ, PO, BJ.

Funding information

The study did not receive any funding.

Compliance with ethical standards

The authors have no financial or proprietary interest in the subject matter or materials discussed in the manuscript. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Conflict of interest

The authors declare that they have no conflicts of interest.

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Copyright information

© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2019

Authors and Affiliations

  1. 1.Department of SurgeryUniversity of Arizona Medical CenterTucsonUSA

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