International Journal of Colorectal Disease

, Volume 34, Issue 7, pp 1259–1265 | Cite as

Outcomes of laparoscopic surgery for pathological T4 colon cancer

  • Tomoaki AokiEmail author
  • Takeru Matsuda
  • Hiroshi Hasegawa
  • Kimihiro Yamashita
  • Yasuo Sumi
  • Ryo Ishida
  • Masashi Yamamoto
  • Shingo Kanaji
  • Taro Oshikiri
  • Tetsu Nakamura
  • Satoshi Suzuki
  • Yoshihiro Kakeji
Original Article



The surgical indication of laparoscopic surgery for pT4 colon cancer remains to be established because only a few studies have investigated the short- and long-term outcomes of laparoscopic surgery for them to date. Therefore, we aimed to elucidate the validity of laparoscopic surgery for them.


We retrospectively analyzed 81 patients with pT4 colon cancer who underwent surgical resection with a curative intent at Kobe University Hospital from January 2007 to December 2015. The short- and long-term outcomes were compared between the propensity score–matched patients who underwent laparoscopic colectomy (LAP group, n = 25) and those who underwent open colectomy (OP group, n = 25).


Intraoperative blood loss was significantly less in the LAP group than in the OP group (p = 0.029). Operative time, R0 resection rate, and morbidity did not significantly differ between the two groups. The 5-year overall survival (OS) and the 5-year recurrence-free survival (RFS) did not significantly differ between the propensity score–matched groups. Univariate and multivariate analyses of the entire cohort showed the surgical approach (LAP vs OP) selected was not a significant prognostic factor for OS or RFS.


The short and the long-term outcomes were similar between the LAP and OP groups. Laparoscopic surgery might be a safe and feasible option for pT4 colon cancer patients.


Pathological T4 Colon cancer Laparoscopic surgery Colectomy 



The authors would like to thank Enago ( for the English language review.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Tomoaki Aoki
    • 1
    Email author
  • Takeru Matsuda
    • 2
  • Hiroshi Hasegawa
    • 1
  • Kimihiro Yamashita
    • 1
  • Yasuo Sumi
    • 1
    • 3
  • Ryo Ishida
    • 1
  • Masashi Yamamoto
    • 1
  • Shingo Kanaji
    • 1
  • Taro Oshikiri
    • 1
  • Tetsu Nakamura
    • 1
  • Satoshi Suzuki
    • 1
  • Yoshihiro Kakeji
    • 1
  1. 1.Division of Gastrointestinal Surgery, Department of SurgeryKobe University Graduate School of MedicineKobeJapan
  2. 2.Division of Minimally Invasive Surgery, Department of SurgeryKobe University Graduate School of MedicineKobeJapan
  3. 3.Division of Gastrointestinal Surgery, Department of SurgeryAsahikawa Medical UniversityAsahikawaJapan

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