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International Journal of Colorectal Disease

, Volume 34, Issue 1, pp 85–95 | Cite as

Mortality after emergency treatment of colorectal cancer and associated risk factors—a nationwide cohort study

  • Thea Helene DegettEmail author
  • Susanne Oksbjerg Dalton
  • Jane Christensen
  • Jes Søgaard
  • Lene Hjerrild Iversen
  • Ismail Gögenur
Original Article

Abstract

Purpose

The aim of this study was to investigate if postoperative mortality after acute surgical treatment of colorectal cancer has decreased in Denmark during this period and to investigate risk factors associated with early death.

Methods

This is a nationwide and population-based cohort study. From the Danish Colorectal Cancer Group database and National Patient Registry, we collected data on all patients operated with bowel resection, diverting stoma only, or placement of an endoscopic stent from 2005 to 2015. Year of surgery was the main exposure variable and 90-day postoperative mortality the primary outcome.

Results

We included 6147 patients. The incidence of patients per year was stable during 2005–2015. The 90-day mortality decreased from 31% in 2005 to 24% in 2015 with a significant time trend (p < 0.0001). Other factors associated with postoperative mortality were increasing age, presence of comorbidity (measured as Charlson comorbidity index score ≥ 1), and stage IV disease. Insertion of self-expanding metallic stent was protective for 90-day postoperative mortality compared with other surgical procedures.

Conclusion

Ninety-day postoperative mortality from acute colorectal surgery has improved in Denmark from 2005 to 2015. Nevertheless, almost one out of four patients undergoing acute surgery for colorectal cancer dies within 90 days.

Keywords

Colorectal Cancer Emergency Surgery 

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Thea Helene Degett
    • 1
    • 2
    Email author
  • Susanne Oksbjerg Dalton
    • 3
  • Jane Christensen
    • 1
  • Jes Søgaard
    • 1
    • 4
  • Lene Hjerrild Iversen
    • 5
    • 6
  • Ismail Gögenur
    • 2
    • 6
  1. 1.Documentation and Quality DepartmentDanish Cancer SocietyCopenhagenDenmark
  2. 2.Centre for Surgical Science (CSS)Zealand University HospitalKøgeDenmark
  3. 3.Unit of SurvivorshipDanish Cancer Society Research CentreCopenhagenDenmark
  4. 4.Institute of Clinical MedicineUniversity of Southern DenmarkOdenseDenmark
  5. 5.Department of Surgery, Section of ColoproctologyAarhus University HospitalAarhusDenmark
  6. 6.Danish Colorectal Cancer GroupCopenhagenDenmark

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