The role of body composition in diverticular disease
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Diverticular disease is a common, chronic inflammatory disease of the bowel. This study investigates the differences in body composition between patients with diverticular disease and those without.
Appropriate patients were identified using a search of the radiology database. Demographic and disease information was gathered using scanned medical records. Body composition analysis was performed at level L3 using single-slice computed tomography techniques.
Two hundred seventy-one patients were included in this study: 83 controls, 93 with diverticulosis and 95 with diverticulitis. Diverticulitis and diverticulosis were associated with a significantly higher visceral fat area (VFA), than the control group (p < 0.001, p < 0.001). Diverticulitis and diverticulosis were associated with a significantly higher visceral fat area to subcutaneous fat area ratio (VFA:SCFA), than the control group (p = 0.005, p = 0.019). Only diverticulosis was associated with increased levels of extramyocellular fat, when compared to the control group (p = 0.001).
Diverticular disease is associated with a higher amount and a higher proportion of visceral fat than seen in controls without diverticular disease.
KeywordsDiverticulosis Diverticulum Extramyocellular fat Visceral fat Body composition
The authors acknowledge with gratitude the valuable advice from A/Prof Frances Milat (Monash Health, Monash University, Hudson Institute) and A/Prof Amanda Vincent (Monash Health, Monash University) regarding body composition alterations in disease.
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