Differences with experienced nurse assistance during colonoscopy in detecting polyp and adenoma: a randomized clinical trial
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This study aims to evaluate whether the participation of an experienced endoscopy nurse in colonoscopy increases the polyp detection rate (PDR) and adenoma detection rate (ADR) of experienced colonoscopists.
This study was a randomized controlled trial. Patients were randomly assigned to the experienced colonoscopist alone (single observer) group, or experienced nurse participation (dual observer) group. The primary outcome was the PDR and ADR. The advanced lesion detection rate was also recorded.
A total of 587 patients were included in the analysis. Among these patients, 291 patients were assigned to the single observer group, while 296 patients were assigned to the dual observer group. The PDR was 33% in the single observer group and 41.9% in the dual observer group (P = 0.026), while the ADR was 23.0% in the single observer group and 30.4% in the dual observer group (P = 0.043). No significant difference was found for advanced lesions between groups.
The present data demonstrated that experienced nurse observation during colonoscopy can improve polyp and adenoma detection rates, even if the colonoscopist is experienced.
Clinicaltrials.gov No. NCT02292563. https://clinicaltrials.gov/ct2/results?cond=&term=NCT02292563&cntry=&state=&city=&dist=
KeywordsNurse assistance Polyp detection Adenoma detection, colorectal cancer
The authors thank Dr. Chunjiu Hu, Dr. Honghui Chen, Dr. Xiaoyun Ding, and Dr. Haizhong Jiang at Ningbo First Hospital, Ningbo, China, for their valuable work in colonoscopy examination and data collection.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
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