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Suicide risk among colorectal cancer patients in Lithuania

  • Audrius DulskasEmail author
  • Ausvydas Patasius
  • Auguste Kaceniene
  • Vincas Urbonas
  • Giedre Smailyte
Short Communication
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Abstract

Purpose

We aimed to estimate suicide risk among colorectal cancer patients in the country showing the highest suicide rates among developed countries.

Methods

Patients with colorectal cancer diagnosed between 1998 and 2012 were identified from the Lithuanian Cancer Registry. Standardised mortality ratios (SMRs) for suicide were calculated for patients diagnosed with cancer in Lithuania, relative to suicide rates in the general population.

Results

Twenty thousand seven hundred sixty-five primary colorectal cancer cases diagnosed between 1998 and 2012 were extracted from the database. Among 19,409 first primary colorectal cancer patients, we identified 67 suicides and the expected number of suicides calculated from general population was 41.4 in this cohort, resulting in an SMR of 1.62 for both sexes (95% CI, 1.27–2.06). A higher suicide risk was found for women (SMR 2.15; 95% CI 1.35–3.41), than for men (SMR 1.48; 95% CI 1.12–1.96). The suicide risk was almost twice higher in patients 60 and older, with highest increase in the oldest patients (SMR 2.12, 95% CI 1.01–4.46). The risk of suicide was not significantly elevated in colorectal cancer patients with localised tumours, but there was a fourfold increase in risk in patients with stage IV tumours. Compared with the general population, the risk of suicide among colorectal cancer patients was four times higher during the first 3 months after diagnosis and decreased thereafter.

Conclusions

The patients with colorectal cancer have a higher rate of suicide compared with the general Lithuanian population. Sex, age, advanced rectal cancer and distant spread of disease were the main predictors of suicide among colorectal cancer patients.

Keywords

Colorectal cancer Suicide Predictors Population-based study 

Notes

References

  1. 1.
    Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 68:394–424.  https://doi.org/10.3322/caac.21492 CrossRefGoogle Scholar
  2. 2.
    Center MM, Jemal A, Ward E (2009) International trends in colorectal cancer incidence rates. Cancer Epidemiol Biomark Prev 18:1688–1694CrossRefGoogle Scholar
  3. 3.
    Poskus E, Kryzauskas M, Poskus T, Mikalauskas S, Samalavicius NE, Aliosin O, Dailidenas S, Tamelis A, Saladzinskas Z, Lizdenis P, Jakaitiene A, Smailyte G, Strupas K (2018) Improved perioperative care is associated with improved long-term survival in colorectal cancer. Int J Color Dis 33:779–785CrossRefGoogle Scholar
  4. 4.
    Kaceniene A, Krilaviciute A, Kazlauskiene J, Bulotiene G, Smailyte G (2017) Increasing suicide risk among cancer patients in Lithuania from 1993 to 2012: a cancer registry-based study. Eur J Cancer Prev 26:S197–S203CrossRefGoogle Scholar
  5. 5.
    Park SA, Chung SH, Lee Y (2016) Factors associated with suicide risk in advanced cancer patients: a cross-sectional study. Asian Pac J Cancer Prev 17(11):4831–4836Google Scholar
  6. 6.
    Samawi HH, Shaheen AA, Tang PA, Heng DYC, Cheung WY, Vickers MM (2017) Risk and predictors of suicide in colorectal cancer patients: a surveillance, epidemiology, and end results analysis. Curr Oncol 24(6):e513–e517CrossRefGoogle Scholar
  7. 7.
    Sun LM, Lin CL, Hsu CY, Kao CH (2018) Risk of suicide attempts among colorectal cancer patients: a nationwide population-based matched cohort study. Psychooncology 27:2794–2801.  https://doi.org/10.1002/pon.4891 CrossRefGoogle Scholar
  8. 8.
    Pham TT, Talukder AM, Walsh NJ, Lawson AG, Jones AJ, Bishop JL, Kruse EJ (2018) Clinical and epidemiological factors associated with suicide in colorectal cancer. Support Care Cancer.  https://doi.org/10.1007/s00520-018-4354-3
  9. 9.
    Dulskas A, Miliauskas P, Tikuisis R, Escalante R, Samalavicius NE (2016) The functional results of radical rectal cancer surgery: review of the literature. Acta Chir Belg 116:1–10CrossRefGoogle Scholar
  10. 10.
    da Silva GM, Hull T, Roberts PL, Ruiz DE, Wexner SD, Weiss EG, Nogueras JJ, Daniel N, Bast J, Hammel J, Sands D (2008) The effect of colorectal surgery in female sexual function, body image, self-esteem and general health: a prospective study. Ann Surg 248:266–272CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Abdominal and General Surgery and OncologyNational Cancer InstituteVilniusLithuania
  2. 2.Faculty of Health CareUniversity of Applied SciencesVilniusLithuania
  3. 3.Department of SurgeryNational Cancer Institute, Clinic of Internal, Family Medicine and Oncology, Faculty of Medicine, Vilnius UniversityVilniusLithuania
  4. 4.Laboratory of Cancer EpidemiologyNational Cancer InstituteVilniusLithuania
  5. 5.Laboratory of Clinical Oncology, Department of Medical OncologyNational Cancer InstituteVilniusLithuania
  6. 6.Institute of Public Health, Faculty of MedicineVilnius UniversityVilniusLithuania

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