The long-term health-related quality of life in patients operated for choledochal cyst
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Late postoperative complications in choledochal cyst (CC) patients are severe problems that affect the quality of life (QOL). We evaluated the postoperative complications and health-related QOL (HRQOL) of CC patients ≥ 18 years of age.
From April 1984 to January 2018, 114 CC patients underwent definitive surgery at our institution. Seventy-nine patients reached ≥ 18 years of age. The HRQOL was assessed using the Japanese version of the SF-36v2. Eight health domain (physical functioning, role-physical, body pain, general health, role-emotional, vitality, mental health, and social functioning) scores and three component summary [physical component summary, mental component summary (MCS), and role-social component summary] scores were compared between the patients with and without complications (C [+] vs. C [−]).
Thirty-five patients answered the questionnaires. Twelve patients had postoperative complications. Among the eight domains, the score of general health was significantly lower in C [+] patients than in C [−] patients (p = 0.0488). Among the three component scores, the MCS score in C [+] patients was lower than in C [−] patients without significance (p = 0.0953).
The HRQOL of CC patients ≥ 18 years of age was mostly acceptable. However, postoperative complications can impair the sense of well-being and affect the mental health.
KeywordsCholedochal cyst Postoperative complication Health-related quality of life General health Mental health
We thank Mr. Brian Quinn for his comments and help with the manuscript. This study was supported by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (JSPS, nos. 26670765, 16K10466, 16K10094, 16K10095, 16K10434, 16H07090, 17K10555, 17K11514, 17K10183, 17K11515), a Research Grant from the President’s Discretionary Expenses of our University, a Research Grant from The UBE Foundation, a Research Grant from Kawano Masanori Memorial Public Interest Incorporated Foundation for Promotion of Pediatrics, Research Grant from Tateishi Science and Technology Foundation, a Research Grant from Mitsui Life Social Welfare Foundation, and a Research Grant from The Kurata Grants of the Hitachi Global Foundation. Sponsor of Manuscript Submission: Atsuyuki Yamataka, M.D., Ph.D., F.A.A.P. (Hon), Department of Pediatric Surgery, Juntendo University, Tokyo, Japan.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflicts of interest in association with the present study.
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