Pediatric Surgery International

, Volume 34, Issue 11, pp 1225–1231 | Cite as

Risk factors for short-term recurrent intussusception and reduction failure after ultrasound-guided saline enema

  • Gang Shen
  • Chuanguang Zhang
  • Junfeng Li
  • Jing Zhang
  • Yongdong Liu
  • Zheming Guan
  • Qiang HuEmail author
Original Article



To investigate the safety and effectiveness of ultrasound-guided saline enema to treat intussusception and to analyze the risk factors affecting short-term recurrence and reduction failure.

Materials and methods

We selected patients who had undergone intussusception reduction via ultrasound-guided saline enema from January 2010 to December 2017. The overall success rate, overall pathologic intussusception rate, and pathologic intussusception rate were calculated in each group. All the patients were divided into two groups: the successfully reduced group and the failed reduction group. Then, the successfully reduced patients were divided into two groups: the short-term recurrence group and the short-term non-recurrence group. The differences between each of the two sets of groups were analyzed, and the risk factors affecting short-term recurrence and failure of intussusception were analyzed.


During the 8-year study period, a total of 1793 patients with intussusception were treated with ultrasound-guided saline enema reduction in our hospital. Among these patients, 1743 (97.2%) experienced successful reduction, 29 (1.6%) had pathologic intussusception, and 1 experienced perforation. After applying the univariate analysis and logistic regressive multivariate analysis, we found that age above 2 years and the absence of fever were risk factors for the early recurrence of intussusception. Pathologic intussusception was a risk factor for reduction failure.


The overall success rate of ultrasound-guided saline enemas was 97.2%, and the pathologic intussusception rate was 1.6%. Age above 2 years and the absence of fever were risk factors for short-term recurrence, and pathologic intussusception was a risk factor for the failure of reduction.


Intussusception Saline enema Risk factors Short-term recurrence Reduction failure 



This study was funded by Weifang Science and Technology Bureau (Grant number 2016YX001).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

For this type of study formal consent is not required.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Gang Shen
    • 1
  • Chuanguang Zhang
    • 1
  • Junfeng Li
    • 1
  • Jing Zhang
    • 1
  • Yongdong Liu
    • 1
  • Zheming Guan
    • 2
  • Qiang Hu
    • 1
    Email author
  1. 1.Department of Pediatric SurgeryWeifang People’s HospitalWeifangChina
  2. 2.Weifang Medical UniversityWeifangChina

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