Analysis of serial electroencephalographic predictors of seizure recurrence in Rolandic epilepsy
We aimed to assess the relationship between electroencephalography (EEG) markers and seizure recurrence in cases with benign epilepsy with centrotemporal spikes (BECT) in a long-term follow-up study.
We analyzed the data of 52 children with BECT who were divided into 2 groups: the isolated group and recurrence group. The clinical profiles and initial/serial visual EEG recordings of both groups were evaluated. The entire follow-up period ranged from 12 to 65 months.
None of the clinical characteristics differed between the 2 groups. Serial EEGs showed that the appearance of Rolandic spikes in the frontal region was more prevalent in the recurrence group. Moreover, a significant correlation was found between bilateral asynchronous discharges and seizure recurrence. However, on initial EEG of these patients, neither of the EEG features exhibited statistical significance.
The presence of frontal focus and bilateral asynchrony appeared to be hallmarks of BECT patients with higher risk for seizure recurrence.
KeywordsBECT Rolandic epilepsy EEG Seizure
Benign epilepsy with centrotemporal spikes
Magnetic resonance imaging
This work was supported by Wuxi Young Medical Talents (Grant Number QNRC021); Medical Innovation Team of Jiangsu Province (Grant Number CXTDB2017016); and Wuxi Medical Development Discipline (Grant Number FZXK001).
Compliance with ethical standards
Conflict of interest
The authors declare that there is no conflict of interest.
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