Early intraventricular baclofen therapy (IVB) for children with dystonic and dysautonomic storm
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Intrathecal baclofen (ITB) is an effective treatment for managing primary and secondary dystonia. Intraventricular baclofen (IVB) was first developed to allow treating patients in which the use of ITB was difficult due to anatomic anomalies. After that, several studies indicate that intraventricular administration of baclofen, is more effective than ITB in refractory dystonia.
We report three cases of children with acute dystonic and dysautonomic storm, treated with IVB. The clinical outcome was satisfactory. The response to the treatment continued after the pump disconnection, suggesting that in this kind of cerebral dysregulations, short-term IVB is an effective treatment.
Early treatment with IVB may be an effective option in patients with post-anoxic dysautonomic and dystonic storm.
KeywordsIntraventricular baclofen therapy Dystonia Baclofen
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Conflict of interest
The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.
- 1.Albright AL (2006) Intraventricular baclofen infusion for dystonia. Report of two cases. J Neurosurg 105:71–74Google Scholar
- 8.Elkaim LM, Alotaibi NM, Sigal A, Alotaibi HM, Lipsman N, Kalia SK, Fehlings DL, Lozano AM, Ibrahim GM, North American Pediatric DBS Collaboration (2018) Deep brain stimulation for pediatric dystonia: a meta-analysis with individual participant data. Dev Med Child Neurol. https://doi.org/10.1111/dmcn.14063