Child's Nervous System

, Volume 34, Issue 12, pp 2351–2352 | Cite as

Neuromotor rehabilitation in spina bifida: the need of randomized controlled trials

  • Sara La Starza
  • Costanza PazzagliaEmail author
  • Claudia Santilli
  • Claudia Rendeli
  • Luca Padua
Letter to the Editor

Dear Editor:

Spina bifida (SB), a neural tube defect occurring during the first month of gestation, affects approximately 1500 infants born annually. SB manifestations vary depending on the extent of closure failure and on the level of the spinal cord lesion ranging from benign small vertebral defect (SB occulta) to significant protrusion of the meninges and spinal cord within the sac with cerebral spinal fluid (myelomeningocele) [4].

The resulting impairments depend on the level of the lesion and can include muscle weakness, paralysis, impaired deambulation, loss of lower extremity sensation, loss of bladder or bowel function, and neurobehavioral alteration.

Despite the large amount of articles and randomized controlled trials (RCTs) on neurocognitive features, incontinence disorders and quality of life in SB, the indications concerning neuromotor rehabilitation still lack. In order to assess the evidences on rehabilitation in SB, we performed a research on PubMed by using the...



The authors acknowledge Campagnola Benedetta, Chicco Alessia, Cricenti Laura, and Fiori Maria.

Compliance with ethical standards

Conflict of interest

The authors have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Sara La Starza
    • 1
  • Costanza Pazzaglia
    • 1
    Email author
  • Claudia Santilli
    • 2
  • Claudia Rendeli
    • 3
  • Luca Padua
    • 1
    • 2
  1. 1.Geriatrics, Neuroscience, Orthopaedics, Head and Neck Department, IRCCSFondazione Policlinico Universitario A. GemelliRomeItaly
  2. 2.IRCCS Fondazione Don Carlo GnocchiMilanItaly
  3. 3.Spina Bifida Center, Department of Science of the Health of Women and Children, IRCCSFondazione Policlinico Universitario A. GemelliRomeItaly

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