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Child's Nervous System

, Volume 34, Issue 8, pp 1445–1446 | Cite as

Intracerebral juvenile xanthogranuloma: an infrequent involvement of hystiocitosis in children

  • P. Torres Pérez
  • A. Bollar Zabala
  • M. Armendáriz Guezala
  • E. Úrculo Bareño
Letter to the Editor

Dear Editor:

Juvenile xanthogranuloma (JXG) is an uncommon disorder of histiocytic non-Langerhans cell type with cutaneous manifestations, which often occurs in children and usually has a benign clinical course [1]. Extracutaneous involvement is rare (4%), it mainly occurs within the eye, bone, lung, muscles, and liver and even more uncommon, involving the central nervous system (1–2%) [2, 3]; therefore, we consider of interest to present a 6-year-old girl diagnosed with disseminated JXG 5 years ago, who presented an intracerebral tumor during her follow-up.

The diagnosis was incidental, after several episodes of osteomyelitis with acromial pain and fever. A complete study of Rx, TC scan, and positron emission tomography-TC pelvic-chest-bone series showed multiple nodular and hypermetabolic lesions with bone and visceral implication: both lungs, liver, osteolytic lesions in skull bone, iliac blades, ribs, and lumbar vertebral bodies.

A cerebral MRI was performed to complete the...

Notes

Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

References

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of NeurosurgeryHospital Universitario DonostiaSan SebastiánSpain

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