Cell salvage processing of residual cardiopulmonary bypass volume in minimally invasive cardiac surgery

  • Ryosuke Muraki
  • Toshinori TotsugawaEmail author
  • Kazuyuki Nagata
  • Kosuke Nakajima
  • Tomoya Oshita
  • Masahisa Arimichi
  • Hidenori Yoshitaka
  • Taichi Sakaguchi
Original Article


Several reports demonstrated positive effects of processing residual cardiopulmonary bypass volume using a cell salvage device in conventional open heart surgery via sternotomy on hemostasis. The present study aimed to investigate whether cell salvage processing has the same effects on postoperative blood loss and transfusion in minimally invasive cardiac surgery. Between July 2015 and April 2018, 80 consecutive patients undergoing minimally invasive aortic valve replacement via right anterolateral minithoracotomy were enrolled in the present study. Perioperative outcomes and coagulation data of 40 patients who were retransfused with processed cardiopulmonary bypass volumes were compared with those of 40 patients receiving unprocessed residual blood (control group). Postoperative blood loss in patients receiving processed residual blood was significantly less than that in the control group at 6 h (115 ± 50 vs. 73 ± 33 ml, p < 0.001) and 12 h (167 ± 70 vs. 125 ± 67 ml, p = 0.009) after surgery, and the rate of fresh frozen plasma use after surgery was significantly reduced in patients receiving processed residual blood (18 vs. 0%, p = 0.012). In conclusion, processing of residual cardiopulmonary bypass volume reduced postoperative blood loss and postoperative use of fresh frozen plasma and could be useful for hemostasis in minimally invasive cardiac surgery.


Cell salvage device Minimally invasive cardiac surgery Residual cardiopulmonary bypass volume Postoperative blood loss 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Japan KK, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Clinical EngineeringThe Sakakibara Heart Institute of OkayamaOkayamaJapan
  2. 2.Department of Cardiovascular SurgeryThe Sakakibara Heart Institute of OkayamaOkayamaJapan

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