We describe of a unique pattern of cardiac dyssynchrony in a patient with a biventricular physiology and systemic right ventricle (RV): the interventricular dyssynchrony due to a contraction delay between the left ventricle and RV. In the present case, the cineangiography and intracardiac electrocardiography of the RV did not reveal intraventricular dyssynchrony of the RV, but revealed interventricular dyssynchrony. In addition, the pressure curves of the ventricles exhibited time phase differences between the two ventricles. The cardiac resynchronization therapy determining the pacing lead positions based on the idea of interventricular dyssynchrony induced reverse cardiac remodeling in this patient with systemic RV dysfunction.
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The authors wish to express their gratitude to Mr. John Martin for his assistance in preparing the manuscript.
All procedures contributing to this work were performed under given the informed consent, and were complied with the ethical standards of the relevant national guidelines on human experimentation (Japan) and with the Helsinki Declaration of 1975 (as revised in 2008). Also this study was approved by the institutional ethics committees (M25-021). The authors have no financial conflicts of interest to disclose concerning this study.
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Miyazaki, A., Sakaguchi, H., Noritake, K. et al. Interventricular dyssynchrony in a patient with a biventricular physiology and a systemic right ventricle. Heart Vessels 32, 234–239 (2017) doi:10.1007/s00380-016-0876-0
- Congenital heart disease
- Systemic right ventricle
- Interventricular dyssynchrony
- Cardiac resynchronization therapy
- Atrioventricular discordance