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Challenges in urogenital tuberculosis

  • Ekaterina KulchavenyaEmail author
  • Denis Kholtobin
  • Sergey Shevchenko
Topic Paper

Abstract

Purpose

For better understanding of urogenital tuberculosis (UGTB), its clinical spectrum and characteristic features need to be evaluated.

Materials and methods

One hundred and forty-two cases of UGTB patients were analyzed retrospectively. We considered age, gender, symptoms, and diagnostic procedures.

Results

The total of 142 patients were divided into group A (consisted of 93 patients with only urinary TB), group B (consisted of 13 male patients with generalized UGTB, including urinary TB and male genital TB (MGTB). Group C consisted of 36 patients with MGTB. Sixty patients in groups A and B 56.6% had kidney TB third-to-fourth stages, which are incurable for anti-TB therapy and require surgery. The urinary tract was involved in 48 patients (45.3%): 25 (23.6%) had ureteral TB and 23 (21.7%) had also bladder TB. The most common symptom for kidney TB was flank pain (69.8%) followed by dysuria (47.2%). Perineal pain and dysuria were most common symptoms for prostate TB and were found in 87.5% (14 patients) and 56.3% (9 patients), respectively. Of total, in only 58 UGTB patients (40.8%), the culture for Mycobacterium tuberculosis (Mtb) was positive.

Conclusion

Of 142 patients with UGTB, 106 (74.7%) had kidney TB and 13 (9.2%) of them had kidney TB in combination with MGTB. Only MGTB (prostate, scrotal, or generalized) was diagnosed in 49 (34.5%) patients. The most common symptoms were flank pain and dysuria. Identification of Mtb in UGTB is difficult. Therefore, the most advanced microbiological technology should be used to establish the correct diagnosis.

Keywords

Urogenital infections Urogenital tuberculosis Kidney tuberculosis Male genital tuberculosis Prostate tuberculosis Mycobacterium tuberculosis Epidemiology of tuberculosis 

Notes

Acknowledgements

Kurt G. Naber assisted revising the manuscript.

Author contributions

EK: project development, data analysis, and manuscript writing. SS: data collection and data analysis. DK: data collection.

Compliance with ethical standards

Conflict of interest

The authors declare no conflict of interest.

Ethical approval

This study was approved by Ethical Committee of Novosibirsk Research TB Institute, Novosibirsk, Russian Federation.

Informed consent

As the study was retrospective, informed consent was not required.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Novosibirsk Research TB Institute, Urogenital ClinicNovosibirskRussian Federation
  2. 2.Novosibirsk State Medical University NovosibirskNovosibirskRussian Federation

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