Real-time MR-guided brain biopsy using 1.0-T open MRI scanner
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To evaluate the safety, feasibility and diagnostic performance of real-time MR-guided brain biopsy using a 1.0-T open MRI scanner.
Medical records of 86 consecutive participants who underwent brain biopsy under the guidance of a 1.0-T open MRI scanner with real-time and MR fluoroscopy techniques were evaluated retrospectively. All procedures were performed under local anaesthesia and intravenous conscious sedation. Diagnostic yield, diagnostic accuracy, complication rate and procedure duration were assessed. The lesions were divided into two groups according to maximum diameters: ≤ 1.5 cm (n = 16) and > 1.5 cm (n = 70). The two groups were compared using Fisher’s exact test.
Diagnostic yield and diagnostic accuracy were 95.3% and 94.2%, respectively. The diagnostic yield of lesions ≤ 1.5 cm and > 1.5 cm were 93.8% and 95.7%, respectively. There was no significant difference in diagnostic yield between the two groups (p > 0.05). Mean procedure duration was 41 ± 5 min (range 33–49 min). All biopsy needles were placed with one pass. Complication rate was 3.5% (3/86). Minor complications included three cases of a small amount of haemorrhage. No serious complications were observed.
Real-time MR-guided brain biopsy using a 1.0-T open MRI scanner is a safe, feasible and accurate diagnostic technique for pathological diagnosis of brain lesions. The procedure duration is shortened and biopsy work flow is simplified. It could be considered as an alternative for brain biopsy.
• Real-time MRI-guided brain biopsy using a 1.0-T open MRI scanner is safe, feasible and accurate.
• No serious complications occurred in real-time MRI-guided brain biopsy.
• Procedure duration is shortened and biopsy work flow is simplified.
KeywordsInterventional radiology Biopsy Magnetic resonance imaging Technology Fluoroscopy
Neuro intensive care unit
T1-weighted turbo spin echo
T2-weighted turbo spin echo
This study has received funding by Shandong Science and technology development plan (2014GGH218005).
Compliance with ethical standards
The scientific guarantor of this publication is Chengli Li.
Conflict of interest
The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.
Statistics and biometry
All authors kindly provided statistical advice for this manuscript.
No complex statistical methods were necessary for this paper.
Written informed consent was obtained from all subjects (patients) in this study.
Institutional review board approval was obtained.
• diagnostic or prognostic study
• performed at one institution
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