Is MRI equivalent to CT in the guidance of TAVR? A pilot study
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To compare a comprehensive cardiovascular magnetic resonance imaging (MRI) protocol with contrast-enhanced computed tomography angiography (CTA) for guidance in transcatheter aortic valve replacement (TAVR) evaluation.
Methods and results
Non-contrast three-dimensional (3D) ‘whole heart’ MRI imaging for aortic annulus sizing and measurements of coronary ostia heights, contrast-enhanced MRI angiography (MRA) for evaluation of transfemoral routes as well as aortoiliofemoral-CTA were performed in 16 patients referred for evaluation of TAVR. Aortic annulus measurements by MRI and CTA showed a very strong correlation (r=0.956, p<0.0001; effective annulus area for MRI 430±74 vs. 428±78 mm2 for CTA, p=0.629). Regarding decision for valve size there was complete consistency between MRI and CTA. Moreover, vessel luminal diameters and angulations of aortoiliofemoral access as measured by MRA and CTA showed overall very strong correlations (r= 0.819 to 0.996, all p<0.001), the agreement of minimal vessel diameter between the two modalities revealed a bias of 0.02 mm (upper and lower limit of agreement: 1.02 mm and -0.98 mm).
In patients referred for TAVR, MRI measurements of aortic annulus and minimal aortoiliofemoral diameters showed good to excellent agreement. Decisions based on MRI measurements regrading prosthesis sizing and transfemoral access would not have modified TAVR-strategy as compared to a CTA-based choice.
• ‘Whole heart’ MRI and CTA measurements of aortic annulus correlate very strongly.
• MRI- and CTA-based prostheses sizing are in excellent agreement.
• MRA and CTA equally guide TAVR access strategy.
KeywordsCardiac imaging techniques Magnetic resonance angiography Aortic valve Contrast media CT angiography
Computed tomography angiography
Estimated Glomerular filtration rate
Intra-class correlation coefficients
Left main artery
Magnetic resonance angiography
Magnetic resonance imaging
Nephrogenic systemic fibrosis
Right coronary artery
Steady-state free precession
Transcatheter aortic valve replacement
The authors state that this work has not received any funding.
Compliance with ethical standards
The scientific guarantor of this publication is Agnes Mayr, MD.
Conflict of interest
The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.
Statistics and biometry
No complex statistical methods were necessary for this paper.
Institutional Review Board approval was obtained.
Written informed consent was obtained from all subjects (patients) in this study.
• diagnostic or prognostic study
• performed at one institution
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