Solitary fibrous tumour of the spine: imaging features of a commonly misdiagnosed entity
- 378 Downloads
Solitary fibrous tumours (SFTs) occurring in the spine are rare. Herein, we review the clinical and imaging data of spinal SFT.
We retrospectively analysed eight cases of pathologically confirmed spinal SFT imaging and clinical data, pathological manifestations, surgical methods, and follow-up results.
Five SFTs cases occurred in the cervical spine, two in the thoracic spine, and one in the lumbosacral spine. Five cases showed a dumbbell-shaped or lobulated soft tissue mass that grew across the intervertebral foramen, two cases showed an expansive intraosseous mass formation in the vertebral body and/or posterior element, and one case showed a long-spindle shaped intraspinal canal mass growing along the spinal canal. Seven caused local invasion and destruction of the vertebral body and posterior element. Benign SFTs displayed a good prognosis, whereas malignant SFTs were prone to recurrence and metastasis (3/4).
Spinal SFTs are difficult to characterise with imaging and required pathological and immunohistochemical investigation. Prolonged follow-up is recommended once a diagnosis of spinal SFTs has been established because of the unclear biology.
• Spinal solitary fibrous tumours are extremely rare.
• SFTs should be showed the differential of masses developing though the foramen.
• Combing imaging with pathology and immunochemistry assesses the diagnosis and establish nature.
KeywordsTomography X-ray computed Magnetic resonance imaging Solitary fibrous tumours Spine
Clinical tumour volume
Gross total resection
Gross tumour volume
Planning gross tumour volume
Planning target volume
Solitary fibrous tumour
This study has received funding by National Natural Science Foundation of China (81701648) and Beijing Municipal Natural Science Foundation (7164309) and National Natural Science Foundation of China(81471634).
Compliance with ethical standards
The scientific guarantor of this paper is professor Min-Ying Su. 164 Irvine Hall, Center for Functional Onco-Imaging, University of California, Irvine,CA 92697-5020. E-mail: email@example.com
Conflict of interest
The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
Statistics and biometry
No complex statistical methods were necessary for this paper.
Written informed consent was obtained from all subjects (patients) in this study.
Institutional Review Board approval was obtained.
• Diagnostic or prognostic study
• Performed at one institution
- 1.Klemperer PRC (1931) Primary neoplasms of the pleura: report of five cases. Arch Pathol (Chic) 11:385–412Google Scholar
- 17.Miyashita K, Hayashi Y, Fujisawa H et al (2004) Recurrent intracranial solitary fibrous tumor with cerebrospinal fluid dissemination. Case report. J Neurosurg 101(6):1045–1048Google Scholar