Porous conductive and biocompatible scaffolds on the basis of polycaprolactone and polythiophene for scaffolding

  • Raana Sarvari
  • Bakhshali MassoumiEmail author
  • Amir ZarehEmail author
  • Younes Beygi-Khosrowshahi
  • Samira Agbolaghi
Original Paper


The fabrication of novel scaffolds was represented on the basis of conductive and biodegradable copolymers. The star-like polycaprolactone (S-PCL) was synthesized from dipentaerythritol as a core by a catalyst of Sn(oct)8 through ring-opening technique. After functionalization of S-PCL by thiophene, thiophene monomer was polymerized from polycaprolactone ends via chemical oxidation polymerization to reach star-like polycaprolactone–polythiophene (S-PCL–PTh). The scaffolds demonstrated a porous configuration (160–190 nm) having the great surface area as well as conductivity of 0.011 S cm−1. The cytocompatibility measurements exhibited that the nanofibers were not toxic to the MG63 cells.


Star-like copolymer Polythiophene Polycaprolactone Nanofiber Tissue engineering 



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© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Stem Cell and Regenerative Medicine InstituteTabriz University of Medical SciencesTabrizIslamic Republic of Iran
  2. 2.Department of ChemistryPayame Noor UniversityTehranIslamic Republic of Iran
  3. 3.Chemical Engineering Department, Faculty of EngineeringAzarbaijan Shahid Madani UniversityTabrizIslamic Republic of Iran

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