Stress resilience and survival among cancer patients: is there any absolute truth?
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Chronic stress has been reported to have an impact on cancer progression . Recently, stress resilience in late adolescence has been connected with survival among patients suffering from cancer . Low compared with high stress resilience has been linked to increased mortality in cancer patients . It has been observed that individual variations in stress resilience may influence survival among men with some types of cancer . It has been indicated that there is a significant relationship between low stress resilience and mortality among men suffering from cancer, particularly oropharyngeal cancer, upper respiratory tract cancers, prostate cancer, and Hodgkin lymphoma . To date, the potential influence of stress susceptibility on cancer progression still remains unknown . Formerly, chronic stress has been described to trigger tumor growth and angiogenesis in a mouse model of ovarian cancer through activation of the tumor cell cyclic AMP(cAMP)–protein kinase A...
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The author declares no potential conflicts of interest.
- 2.Thaker PH, Han LY, Kamat AA, Arevalo JM, Takahashi R, Lu C, Jennings NB, Armaiz-Pena G, Bankson JA, Ravoori M, Merritt WM, Lin YG, Mangala LS, Kim TJ, Coleman RL, Landen CN, Li Y, Felix E, Sanguino AM, Newman RA, Lloyd M, Gershenson DM, Kundra V, Lopez-Berestein G, Lutgendorf SK, Cole SW, Sood AK (2006) Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med 12(8):939–944 (Epub 2006 Jul 23) CrossRefGoogle Scholar
- 3.Powell ND, Sloan EK, Bailey MT, Arevalo JM, Miller GE, Chen E, Kobor MS, Reader BF, Sheridan JF, Cole SW (2013) Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis. Proc Natl Acad Sci USA. 110(41):16574–16579CrossRefGoogle Scholar
- 5.Schrepf A, Clevenger L, Christensen D, DeGeest K, Bender D, Ahmed A, Goodheart MJ, Dahmoush L, Penedo F, Lucci JA 3rd, Ganjei-Azar P, Mendez L, Markon K, Lubaroff DM, Thaker PH, Slavich GM, Sood AK, Lutgendorf SK (2013) Cortisol and inflammatory processes in ovarian cancer patients following primary treatment: relationships with depression, fatigue, and disability. Brain Behav Immun 30(Suppl):S126–S134CrossRefGoogle Scholar
- 10.Nikakhlagh S, Ranjbari N, Khorami E, Saki N (2015) Association between serum levels of interleukin-6 and stage of laryngeal cancer. Iran J Otorhinolaryngol. 27(80):199–205Google Scholar