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Annals of Hematology

, Volume 98, Issue 10, pp 2357–2366 | Cite as

Comparison of quality of life and health behaviors in survivors of acute leukemia and the general population

  • Koung Jin Suh
  • Dong-Yeop Shin
  • Inho Kim
  • Sung-Soo Yoon
  • Jeong-Ok Lee
  • Soo-Mee Bang
  • Ja Min Byun
  • Ki Hwan Kim
  • Jin Hyun Park
  • Sang Min Park
  • Youngae Kim
  • Young Ho Yun
  • Youngil KohEmail author
Original Article

Abstract

We aimed to compare the health-related quality of life and health behaviors of acute leukemia (AL) survivors with that of the general population from two cohorts. AL survivors (n = 149) completed a set of questionnaires to evaluate quality of life, mental status, and health behaviors. AL survivors had more physical and mental difficulties (problems with usual activities, 15% vs. 5%, p < 0.001; anxiety or depression, 24% vs. 9%, p < 0.001; pain, 35% vs. 20%, p = 0.002) and more financial difficulties (p < 0.001) than the general population. Survivors who received stem cell transplantation (SCT) had significantly worse problems with role functioning, fatigue, pain, dyspnea, and insomnia, and had higher depression scores than chemotherapy group (p = 0.024). In terms of health behaviors, AL survivors had lower rates of smoking and drinking and higher influenza vaccination rates than the general population. However, only 17% of survivors had been recommended to receive screening for other cancers from health-care providers, and 67% thought their risk for other cancers was equal or lower than that of the general population. Cancer screening rates were even lower in the SCT group than in the chemotherapy group (p = 0.041). Our study indicates that clinicians should establish more appropriate survivorship care plans.

Keywords

Health-related quality of life Acute leukemia Hematopoietic stem cell transplantation 

Notes

Funding

This study was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI14C1277).

Compliance with ethical standards

The institutional review boards of the participating institutions approved the study, and informed consent was obtained from all subjects.

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

277_2019_3760_MOESM1_ESM.docx (19 kb)
ESM 1 (DOCX 18 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Koung Jin Suh
    • 1
  • Dong-Yeop Shin
    • 2
  • Inho Kim
    • 2
    • 3
  • Sung-Soo Yoon
    • 2
    • 3
  • Jeong-Ok Lee
    • 1
  • Soo-Mee Bang
    • 1
  • Ja Min Byun
    • 4
  • Ki Hwan Kim
    • 4
  • Jin Hyun Park
    • 4
  • Sang Min Park
    • 5
  • Youngae Kim
    • 6
  • Young Ho Yun
    • 5
  • Youngil Koh
    • 2
    • 3
    • 7
    Email author
  1. 1.Department of Internal Medicine, Seoul National University Bundang HospitalSeoul National University College of MedicineSeongnamSouth Korea
  2. 2.Department of Internal Medicine, Seoul National University HospitalSeoul National University College of MedicineSeoulSouth Korea
  3. 3.Cancer Research InstituteSeoul National UniversitySeoulSouth Korea
  4. 4.Department of Internal Medicine, Seoul National University Boramae Medical CenterSeoul National University College of MedicineSeoulSouth Korea
  5. 5.Department of Family Medicine, Seoul National University HospitalSeoul National University College of MedicineSeoulSouth Korea
  6. 6.Division of Cancer Management Policy, National Cancer Control InstituteNational Cancer CenterGoyangSouth Korea
  7. 7.Biomedical Research InstituteSeoul National University HospitalSeoulSouth Korea

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