Management of an adult patient with sickle cell disease and acute chest syndrome by veno-venous extracorporeal membrane oxygenation
Letter to the Editor
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A 21-year-old male patient of a sub-Saharan African descent with homozygote sickle cell disease (SCD) on hydroxyurea therapy was transferred from another hospital to our institution with acute respiratory failure. He had a history of multiple vaso-occlusive crises, salmonella sepsis with multiple organ failure, intracranial bleedings requiring surgical evacuation and bone infarction of hips and vertebral bodies. Initially, he had presented at his local hospital with a pain crisis and was treated with fluids and intravenous opioids. Nonetheless, he developed an increasing loss of vigilance and hypoxemia as well as purulent sputum within 1 day. Anti-infective therapy with piperacillin/tazobactam was initiated. Lab chemistry showed intravascular haemolysis, thrombocytopenia and acute renal failure. Upon referral to our institution, the patient was intubated due to respiratory failure and required norepinephrine at a dose of 1000 μg/h to maintain an acceptable mean arterial...
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The authors declare that they have no conflict of interest.
This article does not contain any studies with human participants performed by any of the authors.
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