Juvenile myelomonocytic leukemia: a surprising cause of peri-orbital tumor and squint
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Juvenile myelomonocytic leukemia (JMML) is a rare hemic malignancy in children. It typically presents with fever, skin lesions, hepatosplenomegaly, and hyperleukocytosis with signs of marrow failure . Distracting extramedullary disease may potentially delay diagnosis. Ocular involvement has been rarely reported in JMML, either at disease progression after diagnosis  or at relapse after stem cell transplantation . Our patient is unique as she presented primarily with ocular manifestations while hematologic changes were subtle.
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The authors declare that they have no conflict of interest.
Study involving animals or human subjects
This article does not contain any studies with human participants or animals performed by any of the authors. As such, in our institution, approval by the institutional review board is not needed. On similar terms, informed consent other than medical management is not required.
- 6.Imamura T, Matsuo S, Yoshihara T, Chiyonobu T, Mori K, Ishida H, Nishimura Y, Kasubuchi Y, Naya M, Morimoto A, Hibi S, Imashuku S (2004) Granulocytic sarcoma presenting with severe adenopathy (cervical lymph nodes, tonsils, and adenoids) in a child with juvenile myelomonocytic leukemia and successful treatment with allogeneic bone marrow transplantation. Int J Hematol 80(2):186–189CrossRefGoogle Scholar