World Journal of Surgery

, Volume 43, Issue 2, pp 642–648 | Cite as

A Comparison Between Plastic and Metallic Biliary Stent Placement in Patients Receiving Preoperative Neoadjuvant Chemoradiotherapy for Resectable Pancreatic Cancer

  • Kota Nakamura
  • Masayuki ShoEmail author
  • Takahiro Akahori
  • Minako Nagai
  • Satoshi Nishiwada
  • Kenji Nakagawa
  • Toshihiro Tanaka
  • Kimihiko Kichikawa
  • Tetsuro Tamamoto
  • Masatoshi Hasegawa
  • Akira Mitoro
  • Hitoshi Yoshiji
  • Naoya Ikeda
Original Scientific Report (including Papers Presented at Surgical Conferences)



The optimal stent type in patients receiving preoperative neoadjuvant chemoradiotherapy (NACRT) is uncertain. The present study aimed to compare the clinical effectiveness of biliary metallic stent (MS) and plastic stent (PS) in patients undergoing preoperative NACRT for resectable pancreatic cancer.


This retrospective study included 43 patients who required either biliary MS or PS before initiating NACRT for resectable or borderline resectable pancreatic head cancer. Seventeen patients had MS (MS group), while 23 patients had PS (PS group). All patients received preoperative NACRT, including gemcitabine and concomitant three-dimensional radiation of 54 Gy, and underwent pancreatectomy. Stent patency, surgery postponement, postoperative outcomes, and cost-effectiveness were compared between these groups.


There were no significant differences in baseline demographic or tumor characteristics between the groups. Stent patency was significantly longer in the MS group than in the PS group (p = 0.042). There were no differences in time to surgery, intraoperative characteristics, surgical complications, margin positivity, and pathological response between the groups. Furthermore, the medical cost of maintenance of biliary drainage during NACRT was similar between the groups.


MS placement compared to PS in patients receiving preoperative NACRT provided no significant benefits during the postoperative course of pancreatectomy. However, MS placement was associated with long stent patency while showing no economic disadvantage. Therefore, MS placement may be recommended in patients receiving preoperative NACRT for resectable pancreatic cancer.


Compliance with ethical standards

Conflict of interest

Authors Nakamura, Sho, Akahori, Nagai, Nishiwada, Nakagawa, Tanaka, Kichikawa, Tamamoto, Hasegawa, Mitoro, Yoshiji, and Ikeda have no conflicts of interest or financial ties to disclose.


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Copyright information

© Société Internationale de Chirurgie 2018

Authors and Affiliations

  • Kota Nakamura
    • 1
  • Masayuki Sho
    • 1
    Email author
  • Takahiro Akahori
    • 1
  • Minako Nagai
    • 1
  • Satoshi Nishiwada
    • 1
  • Kenji Nakagawa
    • 1
  • Toshihiro Tanaka
    • 2
  • Kimihiko Kichikawa
    • 2
  • Tetsuro Tamamoto
    • 3
  • Masatoshi Hasegawa
    • 3
  • Akira Mitoro
    • 4
  • Hitoshi Yoshiji
    • 4
  • Naoya Ikeda
    • 1
  1. 1.Department of SurgeryNara Medical UniversityKashiharaJapan
  2. 2.Department of RadiologyNara Medical UniversityKashiharaJapan
  3. 3.Department of Radiation OncologyNara Medical UniversityKashiharaJapan
  4. 4.Third Department of Internal MedicineNara Medical UniversityKashiharaJapan

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