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Aesthetic Plastic Surgery

, Volume 43, Issue 4, pp 1034–1040 | Cite as

Retrobulbar Injection for Hyaluronic Acid Gel Filler-Induced Blindness: A Review of Efficacy and Technique

  • Christopher C. Surek
  • Sayf A. Said
  • Julian D. Perry
  • James E. ZinsEmail author
Original Article Oculoplastic

Abstract

While blindness after hyaluronic acid gel filler injection occurs only very rarely, it represents a devastating complication for the patient and the surgeon. Retrobulbar injection with hyaluronidase is the only known potential means of reversing this adverse event. However, positive outcomes remain anecdotal. We have attempted to review the current literature regarding possible efficacy and detail the indications and technique to be utilized, if hyaluronidase retrobulbar injection is to be attempted.

Level of Evidence V

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Keywords

Fillers Filler-induced blindness Retrobulbar injection Retrobulbar hyaluronidase Hyaluronidase Hyaluronic acid 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflicts of interest to disclose.

Statement of Human and Animal Rights or Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed Consent

For this type of study, informed consent is not required.

Supplementary material

Supplementary material 1 (MP4 107071 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery 2019

Authors and Affiliations

  • Christopher C. Surek
    • 1
  • Sayf A. Said
    • 2
  • Julian D. Perry
    • 3
  • James E. Zins
    • 2
    Email author
  1. 1.Plastic Surgery DepartmentUniversity of Kansas Health SystemKansas CityUSA
  2. 2.Plastic Surgery DepartmentCleveland ClinicClevelandUSA
  3. 3.Cole Eye InstitutionCleveland Clinic FoundationClevelandUSA

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