Aesthetic Plastic Surgery

, Volume 43, Issue 1, pp 147–154 | Cite as

Photobiomodulation Improved the First Stages of Wound Healing Process After Abdominoplasty: An Experimental, Double-Blinded, Non-randomized Clinical Trial

  • Renato Matta RamosEmail author
  • Marion Burland
  • Jefferson Braga Silva
  • Lauren Marquardt Burman
  • Marco Smiderle Gelain
  • Leticia Manoel Debom
  • Jean Michel Bec
  • Mohsen Alirezai
  • Carlos Oscar Uebel
  • Jean Valmier
Original Article Body Contouring



Photobiomodulation is widely studied for its potential benefits in the wound healing process. Numerous scientific studies have highlighted its effect on various phases of wound repair, but clinical validations are few. This comparative trial aims to evaluate the influence of photobiomodulation on the post-abdominoplasty healing process.


Seventeen Caucasian women (aged 18–55) who underwent an abdominoplasty were enrolled in this double-blinded, controlled clinical trial. The postoperative scars were divided into two areas; the right side of the scars was treated with ten sessions of photobiomodulation (consisting in three types of wavelengths). The other part of the scars was used as control and did not receive any additional treatment. Clinical assessments of both parts of the scars were scheduled at 1, 6 and 12 months postoperative.


Within six months following surgery, significantly improved quality of the scars on the treated side compared with the untreated side was reported by patients and experienced professionals according to Vancouver Scar Scale, Patient and Observer Scar Assessment Scale (p < 0.05) and standardized photographs (p < 0.05). At 1 year of follow-up, patients observed no differences between the treated and untreated sides of the scars. This suggests that photobiomodulation appears to play an early role in the wound healing process, accelerating the first stages of cicatrization.


This study statistically validates the positive impact of photobiomodulation treatment on the first stages of the postoperative healing process. Carried out on Caucasians participants only, this study should, however, be performed on a more heterogeneous population to definitively confirm these effects on an international population.

Clinical trial registry

Registro Brasileiro de ensaios clínicos:, Trial RBR-49PK78.

Level of Evidence II

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors


Wound healing Photobiomodulation Phototherapy Abdominoplasty Surgical scar 



There was no funding from either public, private or third sector sources. The company Biolux Medical—France granted the LED devices, and they did not participate in the research protocol, patient’s selection or surgical procedures.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery 2018

Authors and Affiliations

  • Renato Matta Ramos
    • 1
    • 8
    Email author
  • Marion Burland
    • 2
    • 3
  • Jefferson Braga Silva
    • 4
    • 5
  • Lauren Marquardt Burman
    • 1
  • Marco Smiderle Gelain
    • 6
  • Leticia Manoel Debom
    • 1
  • Jean Michel Bec
    • 2
  • Mohsen Alirezai
    • 7
  • Carlos Oscar Uebel
    • 1
  • Jean Valmier
    • 3
    • 7
  1. 1.Plastic Surgery Division of São Lucas Hospital of PontificiaUniversidade Católica do Rio Grande do SulPorto AlegreBrazil
  2. 2.Biolux InstitutePalavas Les Flots, MontpellierFrance
  3. 3.Inserm U1051University of MontpellierMontpellierFrance
  4. 4.Hand and Reconstructive Microsurgery Division of São Lucas Hospital of PontificiaUniversidade Católica do Rio Grande do SulPorto AlegreBrazil
  5. 5.School of MedicinePUCRS UniversityMontpellierFrance
  6. 6.Universidade Federal de Ciências da Saúde de Porto AlegreSan Isidro, LimaPeru
  7. 7.Inserm U1051., INM, Hôpital St EloiUniversity Hospital Center of MontpellierMontpellier Cedex 5France
  8. 8.Bliss Plastic SurgeryPrivate ClinicSan Isidro LimaPeru

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