International Orthopaedics

, Volume 42, Issue 11, pp 2691–2698 | Cite as

Surgical strategy for benign lesions in proximal femur: internal fixation or endoprosthetic replacement

  • Hongyuan Liu
  • Xiang Fang
  • Zeping Yu
  • Yun Lang
  • Yan Xiong
  • Hong DuanEmail author
Original Paper



The purpose of this study was to explore the indications for the two most frequently applied surgical procedures for benign lesions in the proximal femur.


We retrospectively reviewed 142 patients with benign lesions in the proximal femur from January 2010 to January 2015. Internal fixation (IF) was adopted in 110 patients, while endoprosthetic replacement (EPR) was applied in 32 patients. Clinical data, including operation time, blood loss, hospitalization time, and hospitalization expenses, were compared between the groups. Limb mobilization was evaluated by the Musculoskeletal Tumor Society Score-93 (MSTS-93) and Harris Hip Score (HHS). Local recurrences and complications were statistically compared.


The average follow-up was 66 months (range 32–84 months). In the EPR group, operation time and hospitalization time were significantly shorter (p < 0.05 and p < 0.05, respectively), while blood loss and hospitalization expenses were significantly higher (p < 0.05 and p < 0.05, respectively). Functional outcomes of the MSTS-93 and HHS were higher at the three week follow-up in the EPR group (p < 0.001 and p < 0.001, respectively) but lower at 6 months (p = 0.031 and p = 0.042, respectively). No differences were observed in the two scores at three  months (p = 0.261 and p = 0.134, respectively). Local recurrence and complication rates were similar in the two groups (p = 0.895 and p = 0.942, respectively).


The strategy for benign proximal femur lesions should depend on the site, size, initial diagnosis, and thinning degree of cortical bone. IF and EPR both result in satisfactory local control and functional and radiological results, while EPR is more suitable for aggressive and recurrent lesions and serves as an effective measure after IF failure.


Benign lesions Curettage Internal fixation Endoprosthetic replacement Surgical strategy 


Compliance with ethical standards

Ethical approval

All procedures in studies involving human participants were performed in accordance with the ethical standards of the institutional and national research community and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© SICOT aisbl 2018

Authors and Affiliations

  1. 1.Department of Orthopedics, West China HospitalSichuan UniversityChengduPeople’s Republic of China
  2. 2.Department of OrthopedicsPeople’s Hospital of Deyang CityDeyangPeople’s Republic of China

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