Abdominal Radiology

, Volume 44, Issue 9, pp 3069–3077 | Cite as

Uncommon imaging evolutions of focal liver lesions in cirrhosis

  • Federica VernuccioEmail author
  • Roberto Cannella
  • Giorgia Porrello
  • Alberto Calandra
  • Massimo Midiri
  • Alessandro Furlan
  • Giuseppe Brancatelli



The purpose of this article is to describe and illustrate uncommon imaging evolutions of benign (i.e., cyst, hemangioma, focal nodular hyperplasia-like nodules, and hepatic angiomyolipoma) and malignant (i.e., HCC and non HCC malignancies) lesions in a cirrhotic liver. The content highlights relevant pathogenesis and imaging clues for proper differential diagnosis. Revision of prior imaging and knowledge of these scenarios may help the abdominal radiologist to reach a noninvasive diagnosis and direct the patient to the most appropriate clinical management.


Uncommon imaging evolutions of focal liver lesions in cirrhosis may represent a challenge for the abdominal radiologist, with atypical changes in size, and internal vascularization changes that may lead to misdiagnoses.


Hepatocellular carcinoma Magnetic resonance imaging Computed tomography Liver cirrhosis Liver neoplasms 


Compliance with ethical standards


Federica Vernuccio, Roberto Cannella, Giorgia Porrello, Alberto Calandra, Massimo Midiri, Alessandro Furlan, and Giuseppe Brancatelli have no conflicts of interest to disclose for this study. Alessandro Furlan: Research Grant with General Electric; Elsevier/Amirsys author.


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Dipartimento Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza “G.D’Alessandro” (PROMISE)University of PalermoPalermoItaly
  2. 2.University Paris Diderot, Sorbonne Paris CitéParisFrance
  3. 3.I.R.C.C.S. Centro Neurolesi Bonino PulejoMessinaItaly
  4. 4.Dipartimento di Biomedicina, Neuroscienze e Diagnostica avanzata (BIND)University Hospital of PalermoPalermoItaly
  5. 5.Department of RadiologyUniversity of Pittsburgh Medical CenterPittsburghUSA

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