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Abdominal Radiology

, Volume 44, Issue 10, pp 3359–3369 | Cite as

Characterization of adrenal lesions on chemical shift MRI: comparison of 1.5 T and 3 T MRI

  • İlhan HekimsoyEmail author
  • Ezgi Güler
  • Mustafa Harman
  • Nevra Elmas
Kidneys, Ureters, Bladder, Retroperitoneum
  • 33 Downloads

Abstract

Purpose

To compare three chemical shift MRI techniques [two-dimensional (2D) dual gradient echo (dGRE), 3D VIBE, and 3D VIBE-Dixon] at 3 T and 2D dGRE technique at 1.5 T to assess their ability of detecting microscopic fat in adrenal adenomas and differentiating between adenomas and non-adenomas.

Methods

Seventy-eight patients with 97 lesions (78 adenomas, 19 non-adenomas) underwent both 1.5 T and 3 T chemical shift MRI. The Wilcoxon signed-ranked test was used to determine if there was significant difference between the signal intensity index (SII) values of each technique to assess their ability to detect microscopic fat in adrenal adenomas. ROC analysis was performed for the SII values of each technique, the adrenal-to-spleen SI ratio of 2D dGRE technique at 3 T, and the fat fraction values of the 3D VIBE-Dixon technique to identify the optimal threshold for differentiation of adrenal adenomas from non-adenomas.

Results

For detection of microscopic fat, the mean SII value of 2D dGRE technique at 1.5 T was significantly higher than that of the chemical shift imaging techniques at 3 T (p = 0.001). For discrimination of adenomas from non-adenomas, the area under the curve (AUC) and 95% confidence interval values of 2D dGRE technique at 1.5 T and 2D dGRE, 3D VIBE, 3D VIBE-Dixon techniques at 3 T were calculated as 1.00 (1.00–1.00), 0.991 (0.978–1.00), 0.999 (0.995–1.00), 0.993 (0.979–1.00), respectively, for the SII.

Conclusion

Chemical shift MRI at 1.5 T using the 2D dGRE technique provided the most accurate differentiation between adenomas and non-adenomas. However, there was no statistically significant difference between chemical shift imaging techniques at 1.5 T and 3 T.

Keywords

Adrenal adenoma Adrenal glands Chemical shift imaging MRI 

Notes

Compliance with ethical standards

Conflict of interest

The authors have no relevant financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript.

Institutional review board

The institutional review board approved this single-center, prospective, clinical study.

Informed consent

Written informed consent was obtained from all patients included in the study.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • İlhan Hekimsoy
    • 1
    Email author
  • Ezgi Güler
    • 1
  • Mustafa Harman
    • 1
  • Nevra Elmas
    • 1
  1. 1.Department of RadiologyEge University School of MedicineIzmirTurkey

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