Ultrasound-guided percutaneous catheter drainage of various types of ruptured amebic liver abscess: a report of 117 cases from a highly endemic zone of India
- 53 Downloads
To determine the efficacy and safety ultrasound-guided percutaneous catheter drainage (US-PCD) in management of various types of ruptured amebic liver abscess including free rupture (FR) with diffuse intraperitoneal fluid collections (DIFC).
This study analyzed 117 patients with ruptured ALA who underwent US-PCD. The indication for US-PCD was failure to respond to conservative treatment and/or percutaneous needle aspiration.
Majority of patients were locally fermented alcohol abusers (95%), and malnourished (75%). Ninety-eight patients had intraperitoneal rupture including 66 contained rupture (CR) with localized intraperitoneal fluid collection (LIFC) and 32 FR with DIFC. Pleuropulmonary complication was found in 19 patients including 13 pleural and 6 pulmonary. A total of 333 catheters were used to drain 202 abscess cavities and associated fluid collections. US-PCD was technically and clinically successful in all cases. Multiple sessions (median 2; range 2–5) of PCD required with upsizing the catheter (median 14 F; range 14–20 F) and placement of additional catheter in 26 (22%) patients. The patients with FR with DIFC required more number of catheters (p = 0.01) and had longer hospital stay (p = 0.01). No major procedure related complication was observed. Six patients developed secondary bacterial infection; two of them presented with cavito-cutaneous fistula at catheter insertion site, and one with cholangitis due to biliary stricture formation necessitating subsequent endoscopic treatment. Post-procedural death occurred from sepsis in a patient with FR.
US-PCD is a safe and effective mode of treatment for ruptured ALA including FR with DIFCs. We recommend PCD as a first-line therapy for ruptured ALA.
KeywordsAmebic liver abscess Ultrasound-guided percutaneous catheter drainage Ruptured liver abscess Amebic peritonitis Perforated liver abscess
We thank Dr. Alok Ranjan, Assistant Professor, Community and Family Medicine, All India Institute of Medical Sciences, Patna, for performing the statistical analysis.
Compliance with ethical standards
No funding was received for this study.
Conflict of interest
All authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Our institutional review board approved this retrospective study and waived the requirement for informed consent.
- 6.Eggleston FC, Handa AK, Verghese M (1982) Amebic peritonitis secondary to amebic liver abscess. Surgery 91:46–48Google Scholar
- 15.Monga NK, Sood S, Kaushik SP, et al. (1976) Amebic peritonitis. Am J Gastroenterol 66:366–373Google Scholar
- 20.Tandon N, Karak PK, Mukhopadhyay S, Kumar V (1991) Amoebic liver abscess: rupture into retroperitoneum. Abdom Imaging 16:240–242Google Scholar
- 23.Hai AA, Singh A, Mittal VK, Karan GC (1991) Amoebic liver abscess. Review of 220 cases. Int Surg 76:81–83Google Scholar