Abdominal Radiology

, Volume 43, Issue 11, pp 3142–3146 | Cite as

Increased incidence of abnormally located ovary in patients with Mayer–Rokitansky–Küster–Hauser syndrome: a retrospective analysis with magnetic resonance imaging

  • Yue Wang
  • Jingjing LuEmail author
  • Lan ZhuEmail author
  • Rong Chen
  • Bo Jiang
  • Bo Hou
  • Feng Feng
  • Zhengyu Jin



To explore the incidence of abnormally located ovary in patients with Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome as compared to a control group with magnetic resonance imaging.


Pelvic MR images of 83 MRKH patients and 60 age-matched normal females were retrospectively reviewed by two experienced gynecological radiologists in consensus. Characteristics including location of ovary, ovarian volume, and follicle counts were assessed. The incidence of abnormally located ovary was compared between MRKH patients and controls. The ovarian size and follicle counts were compared among three groups: abnormally located ovaries in MRKH patients, eutopic ovaries in MRKH patients, and normal controls.


In total, 166 ovaries of 83 MRKH patients and 120 ovaries of 60 control females were evaluated. Thirty-seven ovaries of 23 MRKH patients (28%, 23/83) were abnormally located, whereas 3 ovaries of three control females (5%, 3/60) were located in abnormal positions (P < 0.001). The mean volume was 9.2 ± 6.3 mL of the abnormally located ovaries in MRKH patients, 7.8 ± 4.0 mL of the eutopic ovaries in MRKH patients, and 8.9 ± 4.8 mL in control females (P > 0.05). No obvious differences were observed with regard to follicle counts among the three groups.


Incidence of abnormally located ovary was significantly increased in patients with MRKH syndrome. Such knowledge is important for infertility treatment, evaluation of pelvic pain, and surgical planning for MRKH patients.


Mayer–Rokitansky–Küster–Hauser syndrome Mullerian duct anomalies Abnormally located ovary Magnetic resonance imaging 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interest.


  1. 1.
    Bombard DS 2nd, Mousa SA (2014) Mayer-Rokitansky-Kuster-Hauser syndrome: complications, diagnosis and possible treatment options: a review. Gynecol Endocrinol 30:618–623CrossRefGoogle Scholar
  2. 2.
    Londra L, Chuong FS, Kolp L (2015) Mayer-Rokitansky-Kuster-Hauser syndrome: a review. Int J Womens Health 7:865–870CrossRefGoogle Scholar
  3. 3.
    Oppelt PG, Lermann J, Strick R, et al. (2012) Malformations in a cohort of 284 women with Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH). Reprod Biol Endocrinol 10:57CrossRefGoogle Scholar
  4. 4.
    Wang Y, Lu J, Zhu L, et al. (2017) Evaluation of Mayer-Rokitansky-Kuster-Hauser syndrome with magnetic resonance imaging: three patterns of uterine remnants and related anatomical features and clinical settings. Eur Radiol. 27:5215–5224CrossRefGoogle Scholar
  5. 5.
    Allen JW, Cardall S, Kittijarukhajorn M, et al. (2012) Incidence of ovarian maldescent in women with mullerian duct anomalies: evaluation by MRI. AJR Am J Roentgenol 198:W381–385CrossRefGoogle Scholar
  6. 6.
    Trinidad C, Tardaguila F, Fernandez GC, et al. (2004) Ovarian maldescent. Eur Radiol 14:805–808CrossRefGoogle Scholar
  7. 7.
    Dietrich JE, Hertweck SP, Bond S (2007) Undescended ovaries: a clinical review. J Pediatr Adolesc Gynecol 20:57–60CrossRefGoogle Scholar
  8. 8.
    Ombelet WGM, DeNeubourg P (2003) Undescended ovary and unicornuate uterus: simplified diagnosis by the use of clomiphene citrate ovarian stimulation and magnetic resonance imaging (MRI). Hum Reprod 8:5Google Scholar
  9. 9.
    Hall-Craggs MA, Williams CE, Pattison SH, et al. (2013) Mayer-Rokitansky-Kuster-Hauser syndrome: diagnosis with MR imaging. Radiology 269:787–792CrossRefGoogle Scholar
  10. 10.
    Preibsch H, Rall K, Wietek BM, et al. (2014) Clinical value of magnetic resonance imaging in patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome: diagnosis of associated malformations, uterine rudiments and intrauterine endometrium. Eur Radiol 24:1621–1627CrossRefGoogle Scholar
  11. 11.
    Pompili G, Munari A, Franceschelli G, et al. (2009) Magnetic resonance imaging in the preoperative assessment of Mayer-Rokitansky-Kuster-Hauser syndrome. Radiol Med 114:811–826CrossRefGoogle Scholar
  12. 12.
    Suh DS, Han SE, Yun KY, et al. (2016) Ruptured hemorrhagic corpus luteum cyst in an undescended ovary: a rare cause of acute abdomen. J Pediatr Adolesc Gynecol 29:e21–24CrossRefGoogle Scholar
  13. 13.
    Dabirashrafi H, Mohammad K, Moghadami-Tabrizi N (1994) Ovarian malposition in women with uterine anomalies. Obstet Gynecol 83:293–294PubMedGoogle Scholar
  14. 14.
    Wharton LR (1959) Two cases of supernumerary ovary and one of accessory ovary, with an analysis of previously reported cases. Am J Obstet Gynecol 78:1101–1119CrossRefGoogle Scholar
  15. 15.
    Lachman MF, Berman MM (1991) The ectopic ovary. A case report and review of the literature. Arch Pathol Lab Med 115:233–235PubMedGoogle Scholar
  16. 16.
    Saksouk FA, Johnson SC (2004) Recognition of the ovaries and ovarian origin of pelvic masses. RadioGraphics 24:S133–S146CrossRefGoogle Scholar
  17. 17.
    Kives SL, Perlman S, Bond S (2004) Ruptured hemorrhagic cyst in an undescended ovary. J Pediatric Surg 39:e4–e6CrossRefGoogle Scholar
  18. 18.
    Van Voorhis BJ, Dokras A, Syrop CH (2000) Bilateral undescended ovaries: association with infertility and treatment with IVF. Fertil Steril 4:1041–1043CrossRefGoogle Scholar

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical CollegeChinese Academy of Medical SciencesBejingPeople’s Republic of China
  2. 2.Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical CollegeChinese Academy of Medical SciencesBejingPeople’s Republic of China

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