Fibrolipomatous hamartoma: MR imaging findings
- 191 Downloads
To analyze the MR imaging features of fibrolipomatous hamartoma (FLH) of nerves.
Design and patients
MR imaging studies from six patients (three men and three women) were retrospectively reviewed by three musculo-skeletal radiologists. In four patients, a biopsy of the nerve lesion was performed. In two patients, biopsy data were unavailable and the diagnosis was based on the clinical history combined with the MR imaging findings.
Results and conclusion
MR imaging demonstrated fusiform nerve enlargement that was caused by fatty proliferation and thickening of nerve bundles. Nerve bundles appeared as serpentine tubular structures, hypoin-tense on both T1- and T2-weighted images. The degree of fatty proliferation varied among patients. In addition, significant variation in the distribution of fat along the course of the nerves was noted. In three patients, FLH followed the branching pattern of the nerves, a characteristic pathologic finding. In two patients, intramuscular fat deposition (biceps and tibialis posterior muscles) was present. MR imaging findings of FLH are typical, allowing a confident diagnosis. The variation of fatty proliferation among patients and involved nerves as well as the tendency of the abnormalities to follow the branching pattern of the nerves is well demonstrated with MR imaging. FLH may present as an isolated nerve lesion, may be associated with intramuscular fat deposition, or may occur as a feature of macrodystrophia lipomatosa (MDL).
Key wordsFibrolipomatous hamartoma Macrodystrophia lipomatosa Magnetic resonance imaging Peripheral nerve disease Lipofibromatous hamartoma Median nerve
Unable to display preview. Download preview PDF.
- 1.Enzinger FM, Weiss SW. Soft tissue tumors, 3th edn. St Louis: Mosby, 1995: 381–423.Google Scholar
- 4.Tsuge K, Ikuta Y. Macrodactyly and fibro-fatty proliferation of the median nerve. Hiroshima Med Sci 1973; 22: 22–28.Google Scholar
- 10.Richter M, Rueger J, Lang C. Lipofibrom des nervus medianus. Un-fallchirurgie 1993; 20: 42–48.Google Scholar