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Skeletal Radiology

, Volume 40, Issue 12, pp 1575–1579 | Cite as

Long-term in-vitro precision of direct digital X-ray radiogrammetry

  • Alvilde DhainautEmail author
  • Mari Hoff
  • Johan Kälvesten
  • Stian Lydersen
  • Kristina Forslind
  • Glenn Haugeberg
Technical Report

Abstract

Objective

Digital X-ray radiogrammetry (DXR) calculates peripheral bone mineral density (BMD) from hand radiographs. The short-term precision for direct DXR has been reported to be highly satisfactory. However, long-term precision for this method has not been examined. Thus, the aim of this study was to examine the long-term in-vitro precision for the new direct digital version of DXR.

Materials and methods

The in-vitro precision for direct DXR was tested with cadaver phantoms on four different X-ray systems at baseline, 3 months, 6 months, and in one machine also at 12 months. At each time point, 31 measurements were performed.

Results

The in-vitro longitudinal precision for the four radiographic systems ranged from 0.22 to 0.43% expressed as coefficient of variation (CV%). The smallest detectable difference (SDD) ranged from 0.0034 to 0.0054 g/cm2.

Conclusions

The in vitro long-term precision for direct DXR was comparable to the previous reported short-term in-vitro precision for all tested X-ray systems. These data show that DXR is a stable method for detecting small changes in bone density during 6–12 months of follow-up.

Keywords

Digital X-ray radiogrammetry Precision Rheumatoid arthritis Osteoporosis Bone mineral density 

Notes

Acknowledgments

We thank Abbott for financial support (unrestricted grant to St. Olavs Hospital) and the technicians Olav Syrtveit (Kristiansand), Nimal Liyanaarachchi (Trondheim), and Helen Nymberg (Helsingborg). This work was supported by research grants from the Competence Development Fund of Southern Norway and Sørlandet Hospital HF to Professor Glenn Haugeberg.

Open Access

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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Copyright information

© The Author(s) 2011

Open AccessThis is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License (https://creativecommons.org/licenses/by-nc/2.0), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  • Alvilde Dhainaut
    • 1
    • 2
    Email author
  • Mari Hoff
    • 1
    • 2
  • Johan Kälvesten
    • 3
  • Stian Lydersen
    • 4
  • Kristina Forslind
    • 5
    • 6
  • Glenn Haugeberg
    • 1
    • 7
  1. 1.INMRheumatology, Norwegian University of Science and TechnologyTrondheimNorway
  2. 2.Department of RheumatologySt. Olav’s HospitalTrondheimNorway
  3. 3.SectraLinköpingSweden
  4. 4.Unit for Applied Clinical Research, Department of Cancer Research and Molecular MedicineNorwegian University of Science and TechnologyTrondheimNorway
  5. 5.Section of RheumatologyHelsingborgs LasarettHelsingborgSweden
  6. 6.Section of Rheumatology at the Institution of Clinical ScienceUniversity HospitalLundSweden
  7. 7.Department of RheumatologySørlandet HospitalKristiansand SNorway

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