Long-term in-vitro precision of direct digital X-ray radiogrammetry
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Digital X-ray radiogrammetry (DXR) calculates peripheral bone mineral density (BMD) from hand radiographs. The short-term precision for direct DXR has been reported to be highly satisfactory. However, long-term precision for this method has not been examined. Thus, the aim of this study was to examine the long-term in-vitro precision for the new direct digital version of DXR.
Materials and methods
The in-vitro precision for direct DXR was tested with cadaver phantoms on four different X-ray systems at baseline, 3 months, 6 months, and in one machine also at 12 months. At each time point, 31 measurements were performed.
The in-vitro longitudinal precision for the four radiographic systems ranged from 0.22 to 0.43% expressed as coefficient of variation (CV%). The smallest detectable difference (SDD) ranged from 0.0034 to 0.0054 g/cm2.
The in vitro long-term precision for direct DXR was comparable to the previous reported short-term in-vitro precision for all tested X-ray systems. These data show that DXR is a stable method for detecting small changes in bone density during 6–12 months of follow-up.
KeywordsDigital X-ray radiogrammetry Precision Rheumatoid arthritis Osteoporosis Bone mineral density
We thank Abbott for financial support (unrestricted grant to St. Olavs Hospital) and the technicians Olav Syrtveit (Kristiansand), Nimal Liyanaarachchi (Trondheim), and Helen Nymberg (Helsingborg). This work was supported by research grants from the Competence Development Fund of Southern Norway and Sørlandet Hospital HF to Professor Glenn Haugeberg.
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