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Applied Microbiology and Biotechnology

, Volume 103, Issue 23–24, pp 9359–9371 | Cite as

Smart fermentation engineering for butanol production: designed biomass and consolidated bioprocessing systems

  • Tao Zhao
  • Yukihiro Tashiro
  • Kenji SonomotoEmail author
Mini-Review
  • 164 Downloads

Abstract

There is a renewed interest in acetone-butanol-ethanol (ABE) fermentation from renewable substrates for the sustainable and environment-friendly production of biofuel and platform chemicals. However, the ABE fermentation is associated with several challenges due to the presence of heterogeneous components in the renewable substrates and the intrinsic characteristics of ABE fermentation process. Hence, there is a need to select optimal substrates and modify their characteristics suitable for the ABE fermentation process or microbial strain. This “designed biomass” can be used to establish the consolidated bioprocessing systems. As there are very few reports on designed biomass, the main objectives of this review are to summarize the main challenges associated with ABE fermentation from renewable substrates and to introduce feasible strategies for designing the substrates through pretreatment and hydrolysis technologies as well as through the establishment of consolidated bioprocessing systems. This review offers new insights on improving the efficiency of ABE fermentation from designed renewable substrates.

Keywords

Designed biomass ABE Renewable substances Process design Consolidated bioprocessing system 

Notes

Funding information

This work was partially supported by JST SICORP Grant Number JPMJSC16E5, Japan.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

References

  1. Abdel-Rahman MA, Tashiro Y, Sonomoto K (2011) Lactic acid production from lignocellulose-derived sugars using lactic acid bacteria: overview and limits. J Biotechnol 156:286–301PubMedGoogle Scholar
  2. Al-Shorgani NK, Hamid AA, Yusoff WMW, Kalil MS (2013) Pre-optimization of medium for biobutanol production by a new isolate of solvent-producing Clostridium. BioResources 8:1420–1430Google Scholar
  3. Amiri H, Karimi K (2015) Improvement of acetone, butanol, and ethanol production from woody biomass using organosolv pretreatment. Bioprocess Biosyst Eng 38:1959–1972PubMedGoogle Scholar
  4. Amiri H, Karimi K, Zilouei H (2014) Organosolv pretreatment of rice straw for efficient acetone, butanol, and ethanol production. Bioresour Technol 152:450–456PubMedGoogle Scholar
  5. Andrić P, Meyer AS, Jensen PA, Dam-Johansen K (2010) Reactor design for minimizing product inhibition during enzymatic lignocellulose hydrolysis: I. Significance and mechanism of cellobiose and glucose inhibition on cellulolytic enzymes. Biotechnol Adv 28:308–324PubMedGoogle Scholar
  6. Arantes V, Saddler JN (2011) Cellulose accessibility limits the effectiveness of minimum cellulase loading on the efficient hydrolysis of pretreated lignocellulosic substrates. Biotechnol Biofuels 4:3PubMedPubMedCentralGoogle Scholar
  7. Arifin Y, Tanudjaja E, Dimyati A, Pinontoan R (2014) A second generation biofuel from cellulosic agricultural by-product fermentation using Clostridium species for electricity generation. Energy Procedia 47:310–315Google Scholar
  8. Bahrin EK, Baharuddin AS, Ibrahim MF, Abdul Razak MN, Sulaiman A, Abd-Aziz S, Hassan MA, Shirai Y, Nishida H (2012) Physicochemical property changes and enzymatic hydrolysis enhancement of oil palm empty fruit bunches treated with superheated steam. BioResources 7:1784–1801Google Scholar
  9. Balan V (2014) Current challenges in commercially producing biofuels from lignocellulosic biomass. ISRN Biotechnol 2014:1–31Google Scholar
  10. Baral NR, Quiroz-Arita CE, Bradley TH (2018) Probabilistic lifecycle assessment of butanol production from corn stover using different pretreatment methods. Environ Sci Technol 52:14528–14537PubMedGoogle Scholar
  11. Baral NR, Shah A (2014) Microbial inhibitors: formation and effects on acetone-butanol-ethanol fermentation of lignocellulosic biomass. Appl Microbiol Biotechnol 98:9151–9172PubMedGoogle Scholar
  12. Bellido C, Lucas S, González-Benito G, García-Cubero MT, Coca M (2018) Synergistic positive effect of organic acids on the inhibitory effect of phenolic compounds on acetone-butanol-ethanol (ABE) production. Food Bioprod Process 108:117–125Google Scholar
  13. Bharathiraja B, Jayamuthunagai J, Sudharsanaa T, Bharghavi A, Praveenkumar R, Chakravarthy M, Yuvaraj D (2017) Biobutanol – an impending biofuel for future: a review on upstream and downstream processing tecniques. Renew Sustain Energy Rev 68:788–807Google Scholar
  14. Bruins ME, Van Hellemond EW, Janssen AEM, Boom RM (2003) Maillard reactions and increased enzyme inactivation during oligosaccharide synthesis by a hyperthermophilic glycosidase. Biotechnol Bioeng 81:546–552PubMedGoogle Scholar
  15. Chilari D, Dimos K, Georgoula G, Paschos T, Mamma D, Louloudi A, Papayannakos N, Kekos D (2017) Bioethanol production from alkali-treated cotton stalks at high solids loading applying non-isothermal simultaneous saccharification and fermentation. Waste and Biomass Valorization 8:1919–1929Google Scholar
  16. Cho DH, Lee YJ, Um Y, Sang BI, Kim YH (2009) Detoxification of model phenolic compounds in lignocellulosic hydrolysates with peroxidase for butanol production from Clostridium beijerinckii. Appl Microbiol Biotechnol 83:1035–1043PubMedGoogle Scholar
  17. Davison BH, Drescher SR, Tuskan GA, Davis MF, Nghiem NP (2006) Variation of S/G ratio and lignin content in a Populus family influences the release of xylose by dilute acid hydrolysis. Appl Biochem Biotechnol 130:427–435Google Scholar
  18. Demiral H, Yildirim ME (2003) Recovery of acetic acid from waste streams by extractive distillation. Water Sci Technol 47:183–188PubMedGoogle Scholar
  19. Dürre P (2007) Biobutanol: An attractive biofuel. Biotechnol J 2:1525–1534PubMedGoogle Scholar
  20. Eisentraut A (2010) Sustainable production of second-generation biofuels: potential and perspectives in major economies and developing countries. Int Energy Agency 221Google Scholar
  21. Ellabban O, Abu-Rub H, Blaabjerg F (2014) Renewable energy resources: current status, future prospects and their enabling technology. Renew Sustain Energy Rev 39:748–764Google Scholar
  22. Furukawa K, Ichikawa S, Nigorikawa M, Sonoki T, Ito Y (2014) Enhanced production of reducing sugars from transgenic rice expressing exo-glucanase under the control of a senescence-inducible promoter. Transgenic Res 23:531–537PubMedGoogle Scholar
  23. Gao K, Boiano S, Marzocchella A, Rehmann L (2014) Cellulosic butanol production from alkali-pretreated switchgrass (Panicum virgatum) and phragmites (Phragmites australis). Bioresour Technol 174:176–181PubMedGoogle Scholar
  24. Gao K, Rehmann L (2014) ABE fermentation from enzymatic hydrolysate of NaOH-pretreated corncobs. Biomass and Bioenergy 66:110–115Google Scholar
  25. Gao M, Tashiro Y, Yoshida T, Zheng J, Wang Q, Sakai K, Sonomoto K (2015) Metabolic analysis of butanol production from acetate in Clostridium saccharoperbutylacetonicum N1-4 using 13C tracer experiments. RSC Adv 5:8486–8495Google Scholar
  26. Gogoi H, Nirosha V, Jayakumar A, Prabhu K, Maitra M, Panjanathan R (2018) Paper mill sludge as a renewable substrate for the production of acetone-butanol-ethanol using Clostridium sporogenes NCIM 2337. Energy Sources, Part A Recover Util Environ Eff 40:39–44Google Scholar
  27. Gottumukkala LD, Haigh K, Görgens J (2017) Trends and advances in conversion of lignocellulosic biomass to biobutanol: microbes, bioprocesses and industrial viability. Renew Sustain Energy Rev 76:963–973Google Scholar
  28. Gupta R, Kumar S, Gomes J, Kuhad RC (2012) Kinetic study of batch and fed-batch enzymatic saccharification of pretreated substrate and subsequent fermentation to ethanol. Biotechnol Biofuels 5:16PubMedPubMedCentralGoogle Scholar
  29. Harrison MD, Zhang Z, Shand K, O’Hara IM, Doherty WOS, Dale JL (2013) Effect of pretreatment on saccharification of sugarcane bagasse by complex and simple enzyme mixtures. Bioresour Technol 148:105–113PubMedGoogle Scholar
  30. He CR, Kuo YY, Li SY (2017) Lignocellulosic butanol production from Napier grass using semi-simultaneous saccharification fermentation. Bioresour Technol 231:101–108PubMedGoogle Scholar
  31. Hou X, From N, Angelidaki I, Huijgen WJJ, Bjerre AB (2017) Butanol fermentation of the brown seaweed Laminaria digitata by Clostridium beijerinckii DSM-6422. Bioresour Technol 238:16–21PubMedGoogle Scholar
  32. Ibrahim MF, Kim SW, Abd-Aziz S (2018) Advanced bioprocessing strategies for biobutanol production from biomass. Renew Sustain Energy Rev 91:1192–1204Google Scholar
  33. Ibrahim MF, Ramli N, Kamal Bahrin E, Abd-Aziz S (2017) Cellulosic biobutanol by Clostridia: challenges and improvements. Renew Sustain Energy Rev 79:1241–1254Google Scholar
  34. Ikeda Y, Park EY, Okuda N (2006) Bioconversion of waste office paper to gluconic acid in a turbine blade reactor by the filamentous fungus Aspergillus niger. Bioresour Technol 97:1030–1035PubMedGoogle Scholar
  35. Jiang Y, Xu C, Dong F, Yang Y, Jiang W, Yang S (2009) Disruption of the acetoacetate decarboxylase gene in solvent-producing Clostridium acetobutylicum increases the butanol ratio. Metab Eng 11:284–291PubMedGoogle Scholar
  36. Jin M, Gunawan C, Uppugundla N, Balan V, Dale BE (2012) A novel integrated biological process for cellulosic ethanol production featuring high ethanol productivity, enzyme recycling and yeast cells reuse. Energy Environ Sci 5:7168Google Scholar
  37. Jones DT, Woods DR (1986) Acetone-butanol fermentation revisited. Microbiol Rev 50:484–524PubMedPubMedCentralGoogle Scholar
  38. Jouzani GS, Taherzadeh MJ (2015) Advances in consolidated bioprocessing systems for bioethanol and butanol production from biomass: a comprehensive review. Biofuel Res J 5:152–195Google Scholar
  39. Kadić A, Lidén G (2017) Does sugar inhibition explain mixing effects in enzymatic hydrolysis of lignocellulose? J Chem Technol Biotechnol 92:868–873Google Scholar
  40. Kihara T, Noguchi T, Tashiro Y, Sakai K, Sonomoto K (2019) Highly efficient continuous acetone–butanol–ethanol production from mixed sugars without carbon catabolite repression. Bioresour Technol Reports 7:100185Google Scholar
  41. Kumar M, Goyal Y, Sarkar A, Gayen K (2012) Comparative economic assessment of ABE fermentation based on cellulosic and non-cellulosic feedstocks. Appl Energy 93:193–204Google Scholar
  42. Leavitt RI (1983) Preparation of proline from algae. U.S. Patent No. 4:390,624Google Scholar
  43. Lee SH, Yun EJ, Kim J, Lee SJ, Um Y, Kim KH (2016) Biomass, strain engineering, and fermentation processes for butanol production by solventogenic Clostridia. Appl Microbiol Biotechnol 100:8255–8271PubMedGoogle Scholar
  44. Leu SY, Zhu JY (2013) Substrate-related factors affecting enzymatic saccharification of lignocelluloses: Our recent understanding. Bioenergy Res 6:405–415Google Scholar
  45. Liao Z, Guo X, Hu J, Suo Y, Fu H, Wang J (2019) The significance of proline on lignocellulose-derived inhibitors tolerance in Clostridium acetobutylicum ATCC 824. Bioresour Technol 272:561–569PubMedGoogle Scholar
  46. Liu D, Yang Z, Wang P, Niu H, Zhuang W, Chen Y, Wu J, Zhu C, Ying H, Ouyang P (2018) Towards acetone-uncoupled biofuels production in solventogenic Clostridium through reducing power conservation. Metab Eng 47:102–112PubMedGoogle Scholar
  47. Liu Z-Y, Yao X, Zhang Q, Liu Z, Wang Z, Zhang Y, Li F (2017) Modulation of the acetone/butanol ratio during fermentation of corn stover-derived hydrolysate by Clostridium beijerinckii strain NCIMB 8052. Appl Environ Microbiol 83:e03386–e03316PubMedPubMedCentralGoogle Scholar
  48. Lu C, Yu L, Varghese S, Yu M, Yang S-T (2017) Enhanced robustness in acetone-butanol-ethanol fermentation with engineered Clostridium beijerinckii overexpressing adh E2 and ctf AB. Bioresour Technol 243:1000–1008PubMedGoogle Scholar
  49. Lü F, Chai L, Shao L, He P (2017) Precise pretreatment of lignocellulose: relating substrate modification with subsequent hydrolysis and fermentation to products and by-products. Biotechnol Biofuels 10:88PubMedPubMedCentralGoogle Scholar
  50. Mariano AP, Dias MOS, Junqueira TL, Cunha MP, Bonomi A, Filho RM (2013) Butanol production in a first-generation Brazilian sugarcane biorefinery: technical aspects and economics of greenfield projects. Bioresour Technol 135:316–323PubMedGoogle Scholar
  51. Meng X, Ragauskas AJ (2014) Recent advances in understanding the role of cellulose accessibility in enzymatic hydrolysis of lignocellulosic substrates. Curr Opin Biotechnol 27:150–158PubMedGoogle Scholar
  52. Menon V, Rao M (2012) Trends in bioconversion of lignocellulose: biofuels, platform chemicals biorefinery concept. Prog Energy Combust Sci 38:522–550Google Scholar
  53. Merino ST, Cherry J (2007) Progress and challenges in enzyme development for biomass utilization. In: Olsson L (ed) Advances in biochemical engineering/biotechnology. 108:95–120Google Scholar
  54. Mitchell WJ (2016) Sugar uptake by the solventogenic Clostridia. World J Microbiol Biotechnol 32:1–10Google Scholar
  55. Moradi F, Amiri H, Soleimanian-Zad S, Ehsani MR, Karimi K (2013) Improvement of acetone, butanol and ethanol production from rice straw by acid and alkaline pretreatments. Fuel 112:8–13Google Scholar
  56. Nigorikawa M, Watanabe A, Furukawa K, Sonoki T, Ito Y (2012) Enhanced saccharification of rice straw by overexpression of rice exo-glucanase. Rice 5:14PubMedPubMedCentralGoogle Scholar
  57. Noguchi T, Tashiro Y, Yoshida T, Zheng J, Sakai K, Sonomoto K (2013) Efficient butanol production without carbon catabolite repression from mixed sugars with Clostridium saccharoperbutylacetonicum N1-4. J Biosci Bioeng 116:716–721PubMedGoogle Scholar
  58. OECD/IEA (2016) International Energy Agency. Energy and Air Pollution, World Energy Outlook-Spec RepGoogle Scholar
  59. Oshiro M, Hanada K, Tashiro Y, Sonomoto K (2010) Efficient conversion of lactic acid to butanol with pH-stat continuous lactic acid and glucose feeding method by Clostridium saccharoperbutylacetonicum. Appl Microbiol Biotechnol 87:1177–1185PubMedGoogle Scholar
  60. Papayannakos N, Kekos D, Paschos T, Dimos K, Lappas A, Mamma D, Kalogiannis K, Louloudi A (2019) Effect of various pretreatment methods on bioethanol production from cotton stalks. Fermentation 5:5Google Scholar
  61. Park SH, Ong RG, Sticklen M (2016) Strategies for the production of cell wall-deconstructing enzymes in lignocellulosic biomass and their utilization for biofuel production. Plant Biotechnol J 14:1329–1344PubMedGoogle Scholar
  62. Patakova P, Linhova M, Rychtera M, Paulova L, Melzoch K (2013) Novel and neglected issues of acetone-butanol-ethanol (ABE) fermentation by clostridia: Clostridium metabolic diversity, tools for process mapping and continuous fermentation systems. Biotechnol Adv 31:58–67PubMedGoogle Scholar
  63. Payne CM, Knott BC, Mayes HB, Hansson H, Himmel ME, Sandgren M, Ståhlberg J, Beckham GT (2015) Fungal cellulases. Chem Rev 115:1308–1448PubMedGoogle Scholar
  64. Pfromm PH, Amanor-Boadu V, Nelson R, Vadlani P, Madl R (2010) Bio-butanol vs. bio-ethanol: A technical and economic assessment for corn and switchgrass fermented by yeast or Clostridium acetobutylicum. Biomass and Bioenergy 34:515–524Google Scholar
  65. Piotrowski JS, Zhang Y, Bates DM, Keating DH, Sato TK, Ong IM, Landick R (2014) Death by a thousand cuts: The challenges and diverse landscape of lignocellulosic hydrolysate inhibitors. Front Microbiol 5:1–8Google Scholar
  66. Qi B, Chen X, Su Y, Wan Y (2011) Enzyme adsorption and recycling during hydrolysis of wheat straw lignocellulose. Bioresour Technol 102:2881–2889PubMedGoogle Scholar
  67. Qureshi N, Saha BC, Cotta MA, Singh V (2013) An economic evaluation of biological conversion of wheat straw to butanol: A biofuel. Energy Convers Manag 65:456–462Google Scholar
  68. Qureshi N, Saha BC, Hector RE, Hughes SR, Cotta MA (2008) Butanol production from wheat straw by simultaneous saccharification and fermentation using Clostridium beijerinckii: Part I-Batch fermentation. Biomass and Bioenergy 32:168–175Google Scholar
  69. Raganati F, Procentese A, Olivieri G, Götz P, Salatino P, Marzocchella A (2015) Kinetic study of butanol production from various sugars by Clostridium acetobutylicum using a dynamic model. Biochem Eng J 99:156–166Google Scholar
  70. Rani V, Mohanram S, Tiwari R, Nain L, Arora A (2014) Beta-glucosidase : key enzyme in determining efficiency of cellulase and biomass hydrolysis. Bioprocess Biotech 5:1–8Google Scholar
  71. Shen H, He X, Poovaiah CR, Wuddineh WA, Ma J, Mann DGJ, Wang H, Jackson L, Tang Y, Neal Stewart J, Chen F, Dixon RA (2012) Functional characterization of the switchgrass (Panicum virgatum) R2R3-MYB transcription factor PvMYB4 for improvement of lignocellulosic feedstocks. New Phytol 193:121–136PubMedGoogle Scholar
  72. Tachon N, Benjelloun-Mlayah B, Delmas M (2016) Organosolv wheat straw lignin as a phenol substitute for green phenolic resins. BioResources 11:5797–5815Google Scholar
  73. Tashiro Y, Takeda K, Kobayashi G, Sonomoto K, Ishizaki A, Yoshino S (2004) High butanol production by Clostridium saccharoperbutylacetonicum N1-4 in fed-batch culture with pH-stat continuous butyric acid and glucose feeding method. J Biosci Bioeng 98:263–268PubMedGoogle Scholar
  74. Tashiro Y, Yoshida T, Noguchi T, Sonomoto K (2013) Recent advances and future prospects for increased butanol production by acetone-butanol-ethanol fermentation. Eng Life Sci 13:432–445Google Scholar
  75. Trindade WR, Santos RG (2017) Review on the characteristics of butanol, its production and use as fuel in internal combustion engines. Renew Sustain Energy Rev 69:642–651Google Scholar
  76. Ujor V, Agu CV, Gopalan V, Ezeji TC (2014) Glycerol supplementation of the growth medium enhances in situ detoxification of furfural by Clostridium beijerinckii during butanol fermentation. Appl Microbiol Biotechnol 98:6511–6521PubMedGoogle Scholar
  77. Van Dyk JS, Pletschke BI (2012) A review of lignocellulose bioconversion using enzymatic hydrolysis and synergistic cooperation between enzymes—factors affecting enzymes, conversion and synergy. Biotechnol Adv 30:1458–1480PubMedGoogle Scholar
  78. Vanderghem C, Boquel P, Blecker C, Paquot M (2010) A multistage process to enhance cellobiose production from cellulosic materials. Appl Biochem Biotechnol 160:2300–2307PubMedGoogle Scholar
  79. Wade M, Li Y-C, Wahl G (2013) NIH Public Access. Nat Rev Cancer 13:83–96PubMedPubMedCentralGoogle Scholar
  80. Wang Y, Gao C, Zheng Z, Liu FM, Zang JY, Miao JL (2015) Immobilization of cold-active cellulase from antarctic bacterium and its use for kelp cellulose ethanol fermentation. BioResources 10:1757–1772Google Scholar
  81. Wang X, Wu Y, Zhou Y (2017a) Transglycosylation, a new role for multifunctional cellulase in overcoming product inhibition during the cellulose hydrolysis. Bioengineered 8:129–132PubMedGoogle Scholar
  82. Wang Y, Ho SH, Yen HW, Nagarajan D, Ren NQ, Li S, Hu Z, Lee DJ, Kondo A, Chang JS (2017b) Current advances on fermentative biobutanol production using third generation feedstock. Biotechnol Adv 35:1049–1059PubMedGoogle Scholar
  83. Weiss ND, Felby C, Thygesen LG (2019) Enzymatic hydrolysis is limited by biomass–water interactions at high-solids: improved performance through substrate modifications. Biotechnol Biofuels 12:1–13Google Scholar
  84. Wu Y, Xue C, Chen L, Yuan W, Bai F (2016) Synergistic effect of calcium and zinc on glucose/xylose utilization and butanol tolerance of Clostridium acetobutylicum. FEMS Microbiol Lett 363:1–7Google Scholar
  85. Xiao Y, Poovaiah C, Coleman HD (2016) Expression of glycosyl hydrolases in lignocellulosic feedstock: An alternative for affordable cellulosic ethanol production. Bioenergy Res 9:1290–1304Google Scholar
  86. Xin L, Guo Z, Xiao X, Peng C, Zeng P, Feng W, Xu W (2019) Feasibility of anaerobic digestion on the release of biogas and heavy metals from rice straw pretreated with sodium hydroxide. Environ Sci Pollut Res 26:19434–19444Google Scholar
  87. Xiong H, Von Weymarn N, Turunen O, Leisola M, Pastinen O (2005) Xylanase production by Trichoderma reesei Rut C-30 grown on L-arabinose-rich plant hydrolysates. Bioresour Technol 96:753–759PubMedGoogle Scholar
  88. Yang M, Kuittinen S, Vepsäläinen J, Zhang J, Pappinen A (2017) Enhanced acetone-butanol-ethanol production from lignocellulosic hydrolysates by using starchy slurry as supplement. Bioresour Technol 243:126–134PubMedGoogle Scholar
  89. Yoshida T, Tashiro Y, Sonomoto K (2012) Novel high butanol production from lactic acid and pentose by Clostridium saccharoperbutylacetonicum. J Biosci Bioeng 114:526–530PubMedGoogle Scholar
  90. Youn SH, Lee KM, Kim KY, Lee SM, Woo HM, Um Y (2016) Effective isopropanol-butanol (IB) fermentation with high butanol content using a newly isolated Clostridium sp. A1424. Biotechnol Biofuels 9:1–15Google Scholar
  91. Zabihi S, Alinia R, Esmaeilzadeh F, Kalajahi JF (2010) Pretreatment of wheat straw using steam, steam/acetic acid and steam/ethanol and its enzymatic hydrolysis for sugar production. Biosyst Eng 105:288–297Google Scholar
  92. Zeng Y, Zhao S, Yang S, Ding SY (2014) Lignin plays a negative role in the biochemical process for producing lignocellulosic biofuels. Curr Opin Biotechnol 27:98–45Google Scholar
  93. Zhang WL, Liu ZY, Liu Z, Li FL (2012) Butanol production from corncob residue using Clostridium beijerinckii NCIMB 8052. Lett Appl Microbiol 55:240–246PubMedGoogle Scholar
  94. Zhang Z, Harrison MD, Rackemann DW, Doherty WOS, O’Hara IM (2016) Organosolv pretreatment of plant biomass for enhanced enzymatic saccharification. Green Chem 18:360–381Google Scholar
  95. Zhao T, Tashiro Y, Zheng J, Sakai K, Sonomoto K (2018) Semi-hydrolysis with low enzyme loading leads to highly effective butanol fermentation. Bioresour Technol 264:335–342PubMedGoogle Scholar
  96. Zhao T, Yasuda K, Tashiro Y, Darmayanti RF, Sakai K, Sonomoto K (2019) Semi-hydrolysate of paper pulp without pretreatment enables a consolidated fermentation system with in situ product recovery for the production of butanol. Bioresour Technol 278:57–65PubMedGoogle Scholar
  97. Zhao X, Cheng K, Liu D (2009) Organosolv pretreatment of lignocellulosic biomass for enzymatic hydrolysis. Appl Microbiol Biotechnol 82:815–827PubMedGoogle Scholar
  98. Zhao X, Zhang L, Liu D (2012) Biomass recalcitrance. Part I: The chemical compositions and physical structures affecting the enzymatic hydrolysis of lignocellulose. Biofuels. Bioprod Biorefining 6:465–482Google Scholar
  99. Zheng J, Tashiro Y, Wang Q, Sakai K, Sonomoto K (2015a) Feasibility of acetone-butanol-ethanol fermentation from eucalyptus hydrolysate without nutrients supplementation. Appl Energy 140:113–119Google Scholar
  100. Zheng J, Tashiro Y, Wang Q, Sonomoto K (2015b) Recent advances to improve fermentative butanol production: Genetic engineering and fermentation technology. J Biosci Bioeng 119:1–9PubMedGoogle Scholar
  101. Zheng J, Tashiro Y, Zhao T, Wang Q, Sakai K, Sonomoto K (2017) Enhancement of acetone-butanol-ethanol fermentation from eucalyptus hydrolysate with optimized nutrient supplementation through statistical experimental designs. Renew Energy 113:580–586Google Scholar
  102. Zhou Y, Wang X, Wei W, Xu J, Wang W, Xie Z, Zhang Z, Jiang H, Wang Q, Wei C (2016) A novel efficient β-glucanase from a paddy soil microbial metagenome with versatile activities. Biotechnol Biofuels 9:36PubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Laboratory of Microbial Technology, Division of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate SchoolKyushu UniversityFukuokaJapan
  2. 2.Energy-rich Compounds Production by Photosynthetic Carbon Fixation Research Center, College of Life ScienceQingdao Agricultural UniversityQingdaoChina
  3. 3.Laboratory of Soil and Environmental Microbiology, Division of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate SchoolKyushu UniversityFukuokaJapan
  4. 4.Laboratory of Microbial Environmental Protection, Tropical Microbiology Unit, Center for International Education and Research of Agriculture, Faculty of AgricultureKyushu UniversityFukuokaJapan

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