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Plea for a standardized imaging approach to disorders of sex development in neonates: consensus proposal from European Society of Paediatric Radiology task force

  • Fred E. AvniEmail author
  • Heloise Lerisson
  • Maria-Luisa Lobo
  • Maryse Cartigny
  • Marcello Napolitano
  • Hans-J. Mentzel
  • Michael Riccabona
  • Magdalena Wozniak
  • Damjana Kljucevsek
  • Thomas A. Augdal
  • Bruno Constanza
  • Donald Ibe
  • Kassa Darge
  • Samuel Stafrace
  • Philippe Petit
  • Lil-Sofie Ording Muller
ESPR
  • 69 Downloads

Abstract

This consensus article elaborated by the European Society for Paediatric Radiology task force on gastrointestinal and genitourinary imaging is intended to standardize the imaging approach in newborns with disorders of sex development. These newborns represent a difficult and stressful situation necessitating a multidisciplinary team approach. Imaging plays an important role in the work-up but needs to be optimized and customized to the patient. Ultrasound plays the central role in assessing the genital anatomy. The examination must be conducted in a detailed and systematic way. It must include transabdominal and transperineal approaches with adapted high-resolution transducers. The pelvic cavity, the genital folds, the inguinal areas and the adrenals must be evaluated as well as the rest of the abdominal cavity. A reporting template is proposed. The indications of magnetic resonance imaging and cysto- and genitography are discussed as well as they may provide additional information. Imaging findings must be reported cautiously using neutral wording as much as possible.

Keywords

Adrenals Congenital anomalies Disorders of sex development Genital tract Magnetic resonance imaging Neonates Sexual differentiation Ultrasound 

Notes

Compliance with ethical standards

Conflicts of interest

None

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019
corrected publication 2019

Authors and Affiliations

  • Fred E. Avni
    • 1
    Email author
  • Heloise Lerisson
    • 1
  • Maria-Luisa Lobo
    • 2
  • Maryse Cartigny
    • 3
  • Marcello Napolitano
    • 4
  • Hans-J. Mentzel
    • 5
  • Michael Riccabona
    • 6
  • Magdalena Wozniak
    • 7
  • Damjana Kljucevsek
    • 8
  • Thomas A. Augdal
    • 9
  • Bruno Constanza
    • 10
  • Donald Ibe
    • 11
  • Kassa Darge
    • 12
  • Samuel Stafrace
    • 13
  • Philippe Petit
    • 14
  • Lil-Sofie Ording Muller
    • 15
  1. 1.Department of Pediatric Imaging Jeanne de Flandre HospitalLille University HospitalsLille- CedexFrance
  2. 2.Department of RadiologyHospital de Santa Maria-CHULNLisbonPortugal
  3. 3.Department of Pediatric Endocrinology Jeanne de Flandre HospitalLille University HospitalsLilleFrance
  4. 4.Department of Pediatric and Neuro-radiology V. Buzzi Children’s HospitalMilanItaly
  5. 5.Department of Pediatric Radiology, Institute of Diagnostic and Inteventional Radiology, University Hospital JenaJenaGermany
  6. 6.Department of Radiology, Division of Pediatric RadiologyUniversity Hospital LKH GrazGrazAustria
  7. 7.Department of Pediatric RadiologyMedical University of LublinLublinPoland
  8. 8.Department of RadiologyUniversity Children’s Hospital LjubljanaLjubljanaSlovenia
  9. 9.Department of RadiologyUniversity Hospital of Northern NorwayTromsøNorway
  10. 10.Department of Radiology AOUIVeronaItaly
  11. 11.Department of RadiologyAhmadu Bello University Teaching HospitalZariaNigeria
  12. 12.Department of Radiologythe Children’s Hospital of PhiladelphiaPhiladelphiaUSA
  13. 13.Department of Medical ImagingSidra MedicineDohaQatar
  14. 14.Department of Prenatal and Pediatric ImagingTimone Children’s HospitalMarseilleFrance
  15. 15.Division of Radiology and Nuclear Medicine, Department of Pediatric RadiologyOslo University Hospital, RikshospitaletOsloNorway

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